One-step synthesis of a dual-functional AIE-active probe for ClO− detection and photodynamic therapy

文献情報

出版日 2024-01-03

DOI 10.1039/D3CC05927H

インパクトファクター 6.222

著者

Yiping Liu, Juan Fu, Jiaxing Wan, Tongsheng Huang, Weifeng Zhu, Jianwen Tian, Xiaoyong Zhang, Yen Wei

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要旨

An amphiphilic fluorescent probe (BHSMP) with aggregation-induced emission (AIE) features was synthesized via a one-step route. The probe showed high water dispersibility, low toxicity and the ability of selective and sensitive (limit of detection of 0.11 µM) detection of ClO− with fast-response (≤30 s) in aqueous solution and living organisms. Owing to the donor–acceptor (D–A) structure and existence of cationic groups, BHSMP could also generate reactive oxygen species under light-irradiation and potentially be utilized for photodynamic therapy. The strategy described in this work is of great significance for the design and synthesis of multifunctional AIE-active functional materials to facilitate their biomedical applications.

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掲載誌

Chemical Communications

CiteScore: 8.6

自己引用率: 4.7%

年間論文数: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

One-step synthesis of a dual-functional AIE-active probe for ClO− detection and photodynamic therapy

文献情報

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関連文献

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Inside front cover

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