Design of (β-diazo-α,α-difluoroethyl)phosphonates and their application as masked carbenes in visible light-promoted coupling reactions with sulfonic acids

文献情報

出版日 2021-01-04

DOI 10.1039/D0QO01394C

インパクトファクター 5.281

著者

Haibo Mei, Jiang Liu, Romana Pajkert, Li Wang, Gerd-Volker Röschenthaler, Jianlin Han

原文を見る

要旨

We elaborate a method for the generation of (2-diazo-1,1-difluoroethyl)phosphonates from (β-amino-α,α-difluoroethyl)phosphonates as precursors and their application as masked carbenes in coupling reactions with sulfonic acids under photochemical conditions. Varieties of coupling partners including aminophosphonates and sulfonic acids are well tolerated in this reaction affording unknown sulfonate esters in good yields. The strategy of this new diazo compound provides a valuable vista for the construction of functionalized difluoromethylene phosphonates and transformations of fluoro diazo compounds.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Design of (β-diazo-α,α-difluoroethyl)phosphonates and their application as masked carbenes in visible light-promoted coupling reactions with sulfonic acids

文献情報

おすすめジャーナル

関連文献

The influence of a 1,1-diarylvinyl moiety on the photochromism of naphthopyrans

Tin(ii) chloride assisted synthesis of N-protected γ-amino β-keto esters through semipinacol rearrangement

Radical formation of amino acid precursors in interstellar regions? Ser, Cys and Asp

Elaboration and properties of hierarchically structured optical thin films of MIL-101(Cr)

Asymmetric epoxidation of 2-arylidene-1,3-diketones: facile access to synthetically useful epoxides

Acid–base properties of functionalised tripodal polyamines and their interaction with nucleotides and nucleic acids

Assembling chirality into magnetic nanowires: cyano-bridged iron(iii)–nickel(ii) chains exhibiting slow magnetization relaxation and ferroelectricity

Asymmetric synthesis of a tricyclic benzofuran motif: a privileged core structure in biologically active molecules

Raman spectroscopy of strained single-walled carbon nanotubes

Synthesis and structure of a magnesium–amidoborane complex and its role in catalytic formation of a new bis-aminoborane ligand

こちらもおすすめ

環戊烷-1,3-二甲酸甲酯はどのように合成されますか？

4-メトキシ-1,2,3-スチアゼ-3,5-ジオンとは何ですか？

プロスタグランジンA2について「に適用される法規ガイドラインは何ですか？'

4-アミノ-1-ナフタレン sulfonic 酸についての物理化学的性質は何ですか？

N-GlcNAc-生物素を取り扱う際の実験室安全事項は何ですか？

3-アミノメチルフローラノピペリジン-1-カルボニル酸テルブチルエステルとは何ですか？

6-溴-1-甲基-1H-ベンゾ[d][1,2,3]三氮唑はどのように合成されますか？

4-硫代尿苷はどのように合成されますか？

ブレインナトリユリックペプチド32ラットとは何ですか？

1-(3-氮杂啶)-4-羟基哌啶双盐酸盐の物理化学的性質は何ですか？

掲載誌

Organic Chemistry Frontiers

おすすめ化合物

6-Bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine

5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde

[4-(Isobutyrylamino)phenyl]boronic acid

4-Hydroxy-3-(2-methyl-2-propanyl)benzonitrile

Ethyl (2-methyl-1H-indol-3-yl)acetate

おすすめサプライヤー