A novel fluorescent-colorimetric probe for Al3+ and Zn2+ ion detection with different response and applications in F− detection and cell imaging

文献情報

出版日 2019-08-08

DOI 10.1039/C9AN01295H

インパクトファクター 4.616

著者

Jiaxin Fu, Yongxin Chang, Bai Li, Huihui Mei, Li Yang

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要旨

A novel Schiff base fluorescence probe (HL) was synthesized by the condensation of salicylaldehyde and an 8-aminoquinoline derivative. This probe acts as a “turn-on” dual selectivity fluorescence probe for Zn2+ and Al3+ ions, providing different colors and detection limits (DL) of 11.5 and 23.5 nM, respectively. Moreover, when Zn2+ and Al3+ co-exist, HL exhibits a preference for Al3+ by displacing Zn2+ from the HL-Zn2+ complex, realizing a dual-channel signal output for Al3+. The HL-Al3+ system could further discern F− by a “turn-off” fluorescence response with a DL of 86.0 nM. Furthermore, the probe HL was capable of monitoring intracellular Al3+, Zn2+ and F− in living PC12 cells in vitro through fluorescence imaging, which proved its value in potential in vivo applications.

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Analyst

CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

A novel fluorescent-colorimetric probe for Al3+ and Zn2+ ion detection with different response and applications in F− detection and cell imaging

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