Ni-Catalyzed 1,2-iminoacylation of alkenes via a reductive strategy

文献情報

出版日 2018-10-25

DOI 10.1039/C8QO01044G

インパクトファクター 5.281

著者

Lin Wang, Chuan Wang

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要旨

In this protocol, we developed a reductive strategy for 1,2-iminoacylation of alkenes. Under the catalysis of the Ni-biquinoline system, various oxime esters incorporating a pendant terminal olefinic unit were successfully reacted with acid chlorides or anhydrides as electrophilic acylating reagents in the presence of Zn as a reductant, furnishing a series of pyrrolines in moderate to excellent yields. This reaction is distinguished by safe and mild reaction conditions that avoid the use of CO gas as a carbonyl source, pregenerated organometallics and strong bases as reaction additives.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Ni-Catalyzed 1,2-iminoacylation of alkenes via a reductive strategy

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