Chemoselective synthesis of m-teraryls through ring transformation of 2H-pyran-2-ones by 2-(1-arylethylidene)-malononitriles

文献情報

出版日 2018-10-31

DOI 10.1039/C8OB02370K

インパクトファクター 3.876

著者

Rahul Panwar, Shally, Ranjay Shaw, Amr Elagamy, Ramendra Pratap

原文を見る

要旨

We have developed a simple, efficient and chemoselective approach for the synthesis of m-teraryls by the reaction of 6-aryl-2-oxo-4-(sec.amino)-2H-pyran-3-carbonitriles and 2-(1-arylethylidene)malononitriles under basic conditions. We used 6-aryl-2-oxo-4-methylsulfanyl-2H-pyran-3-carbonitriles as precursors and successfully afforded 5′-methylsulfanyl-[1,1′;3′,1′′]teraryl-4′-carbonitriles. We tried to understand the difference in the reactivity of structurally symmetrical molecules, such as allyl cyanide, 2-cyanomethylbenzonitrile and 2-(1-arylethylidene)malononitrile. The structure of 4′′-methyl-5′-(piperidin-1-yl)-[1,1′:3′,1′′-terphenyl]-4′-carbonitrile was confirmed by single crystal X-ray diffraction analysis.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Chemoselective synthesis of m-teraryls through ring transformation of 2H-pyran-2-ones by 2-(1-arylethylidene)-malononitriles

文献情報

おすすめジャーナル

関連文献

Surface chemistry and interface science

Modeling the impedance spectra of mixed conducting thin films with exposed and embedded current collectors

Quantitative probing of subtle interactions among H-bonds in alpha hydroxy carboxylic acid complexes

Front cover

Pattern transitions in a compressible floating elastic sheet

Ligand displacement induced morphologies in block copolymer/quantum dot hybrids and formation of core–shell hybrid nanoobjects

DNA protection by ectoine from ionizing radiation: molecular mechanisms

Probe-location dependent resonance energy transfer at lipid/water interfaces: comparison between the gel- and fluid-phase of lipid bilayer

Melting kinetics of superheated crystals of glucose and fructose

Electroluminescence of [Ru(bpy)3]2+ at gold and silver screen-printed electrodes followed by real-time spectroelectrochemistry

こちらもおすすめ

間溴苯甲酰腈の市場動向や研究トレンドはどうですか？

去磺基萝卜硫苷とは何ですか？

Methyl 2-amino-5-(trifluoromethyl)benzoateに適用される法規ガイドラインは何ですか？

3-ブロモ-1,3,4,5-四水化-2H-1-ベンザアゼピン-2-オンは安全ですか？

三氟甲基ピリジン-2-甲アミン塩酸塩は安全ですか？

1-エチル-4-(4-硝基フェニル)ピペリジンは安全ですか？

1,1-ジメトキシプロパン-2-オンは安全ですか？

コバルト(II) 3,3'-{[(1S,2S)-1,2-ジメチルフENCYCLICALE-1,2-エチエンジイル]ビス[ニトロリルメチルイリデン]}ビス[4-オキソ-2-ペンテン-2-olate]について「に適用される法規ガイドラインは何ですか？

「カーバミル酸, N-[8-[[2-[[2-(2,6-ジオキソ-3-ピペリジニル)-2,3-ジオキソ-1,3-ジヒドロ-1H-イソイソインドール-4-イルオキシ]アセチル]アミノ]オクチル]-1,1-ジメチレチルエステル」はどのように保存すればよいですか？

FMoc-D-4-Aph(tBu-CbM)-OHはどのように保存すればよいですか？

掲載誌

Organic & Biomolecular Chemistry

おすすめ化合物

Tris(2,2,3,3,4,4,5,5-octafluoropentyl) phosphate

N,O-Diacetyl-L-tyrosine

(3,4-Difluoro-2-methoxyphenyl)boronic acid

2,4,5-Trichloro-7H-pyrrolo[2,3-d]pyrimidine

Allyl diethyl phosphate

おすすめサプライヤー