Hydrolysis resistant functional polypeptide scaffold for biomaterials

文献情報

出版日 2017-12-21

DOI 10.1039/C7PY01586K

インパクトファクター 5.582

著者

原文を見る

要旨

For biomaterials, rich functionality often comes at a cost of precise control over structure. In this paper, we have developed a hydrolysis resistant polypeptide that marries the potential for expansive modification with synthetic control. This polymer, poly(γ-propargyl-L-glutamine) may be prepared from commercially available or previously synthesized poly(L-glutamate) by routine amide bond coupling reactions on a multi gram scale. Afterwards, the polymer may be altered to suit many applications through modification of the side chains or end group by orthogonal and quantitative reactions. The ease of synthesis and versatile nature of poly(γ-propargyl-L-glutamine) makes it a unique and ideal scaffold for biomaterial applications.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Hydrolysis resistant functional polypeptide scaffold for biomaterials

文献情報

おすすめジャーナル

関連文献

Terpenoids: shape and non-covalent interactions. The rotational spectrum of cis-verbenol and its 1 : 1 water complex

Identification of a receiver triplet state in the ultrafast intersystem crossing of carbonylpyrenes

Front cover

The antibacterial activity of p-tert-butylcalix[6]arene and its effect on a membrane model: molecular dynamics and Langmuir film studies

An in situ exchange mechanism for dye molecules and cations at the nano-semiconductor film/electrolyte interface

Spectroscopic evidence of a particular intermolecular interaction in iodomethane–ethanol mixtures: the cooperative effect of halogen bonding, hydrogen bonding, and the solvent effect

Improving the performance of the MM/PBSA and MM/GBSA methods in recognizing the native structure of the Bcl-2 family using the interaction entropy method

Formation of N2 bubbles along grain boundaries in (ZnO)1−x(GaN)x: nanoscale STEM-EELS studies

Defect engineering, microstructural examination and improvement of ultrafast third harmonic generation in GaZnO nanostructures: a study of e-beam irradiation

DNP NMR spectroscopy of cross-linked organic polymers: rational guidelines towards optimal sample preparation

こちらもおすすめ

2,3-スチオエポキシマドルを取り扱う際の実験室安全事項は何ですか？

6-氟-2-氨基苯酚の主な用途は何ですか？

BOC-S-3-アミニ-4-(4-メチオキシベンチル)-ブタン酸の代替品はありますか？

Methyl 2-(chloromethyl)-3-nitrobenzoate（1218910-61-2）の代替品はありますか？

（2R)-2-アミノ-N-ベンジル-3-ヒドロキシプロパナミドを含む廃棄物はどのように処理すべきですか？

6,7-二氢-咪唑並[1,2-a]ピリドイン-8(5h)-酮はどのように合成されますか？

エチル(3R)-3-ピロリジニル酢酸水和塩とは何ですか？

（2S）-{[(2-メチルエチルオキシ]カルボニル}アミノ)[2-(トリアフルオロメチルフェニル]エチカシック酸の物理化学的性質は何ですか？

2-ブロモ-1-(2-メチル-2-プロパニル)-4-ニトロベンゼンはどのように保存すればよいですか？

1-[(4-硝基フェニル)スルホニル]-1H-1,2,4-三唑の市場動向や研究トレンドはどうですか？

掲載誌

Polymer Chemistry

おすすめ化合物

4-(Bromomethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene

6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-carbaldehyde

5-Dehydroepisterol

(1H-Pyrazol-4-yl)boronic acid hydrochloride

8-Bromo-6-fluoro[1,2,4]triazolo[1,5-a]pyridin-2-amine

おすすめサプライヤー