GAP chemistry for pyrrolyl coumarin derivatives: a highly efficient one-pot synthesis under catalyst-free conditions
文献情報
Xuecheng Liu, Xian Feng, Zhibin Huang, Daqing Shi
A concise and efficient one-pot synthesis of pyrrolyl coumarin derivatives via a four-component reaction of 4-hydroxycoumarin, arylglyoxal monohydrate, dialkyl but-2-ynedioate and amines under catalyst-free conditions in an environmentally friendly medium (ethanol) is described. This synthesis was confirmed to follow the group-assisted-purification (GAP) chemistry process, which can avoid traditional chromatography and recrystallization purification methods.
関連文献
Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry
Cunyu Yan, Jason W. Schmidberger, Fabio Parmeggiani, Shaneela A. Hussain, Nicholas J. Turner, Sabine L. Flitsch, Perdita Barran
DOI: 10.1039/C6AN00617E
An initial estimation method using cosine similarity for multivariate curve resolution: application to NMR spectra of chemical mixtures
Yuya Nagai, Woon Yong Sohn
DOI: 10.1039/C9AN01416K
Can solvent induced surface modifications applied to screen-printed platforms enhance their electroanalytical performance?
Christopher W. Foster, Loanda R. Cumba, Devaney R. do Carmo, Craig E. Banks
DOI: 10.1039/C6AN00440G
Real-time quantitative nicking endonuclease-mediated isothermal amplification with small molecular beacons
Chenguang Wang, Tianxiao Guo
DOI: 10.1039/C6AN00145A
A catalytic DNA circuit-programmed and enzyme-powered autonomous DNA machine for nucleic acid detection
Shuang Liu, Chen Xin, Xiaoxiao Yu, Zhenbo Ding, Shufeng Liu
DOI: 10.1039/C9AN01568J
Correction: Bacterial detection and identification from human synovial fluids on an integrated microfluidic system
Ting-Hang Liu, Shu-Shen Cheng, Huey-Ling You, Mel S. Lee
DOI: 10.1039/C9AN90087J
A novel DNA tetrahedron–hairpin probe for in situ “off–on” fluorescence imaging of intracellular telomerase activity
Qiu-Mei Feng, Meng-Jiao Zhu, Ting-Ting Zhang, Jing-Juan Xu, Hong-Yuan Chen
DOI: 10.1039/C6AN00241B
A near-infrared fluorescent aza-bodipy probe for dual-wavelength detection of hydrogen peroxide in living cells
Jingjing Xu, Jingying Zhai, Yanmei Xu, Jingwei Zhu, Yu Qin, Dechen Jiang
DOI: 10.1039/C6AN00262E
Thermo-responsive polymer aided spheroid culture in cryogel based platform for high throughput drug screening
J. Sarkar, A. Kumar
DOI: 10.1039/C6AN00356G
Spatially resolved endogenous improved metabolite detection in human osteoarthritis cartilage by matrix assisted laser desorption ionization mass spectrometry imaging
M. R. Eveque-Mourroux, P. J. Emans, R. R. M. Zautsen, A. Boonen, R. M. A. Heeren, B. Cillero-Pastor
DOI: 10.1039/C9AN00944B
こちらもおすすめ
2-ヒドロキシ-5-ニトロベンジンブロモイドの代替品はありますか?
2-ヒドロキシ-5-ニトロベンジンブロモイドは特定の化学反応に適しているため、代替品は限られています。しかし、同様の構造を持つ2-ヒドロキシ-4-ニトロベンジン...
N-(2-ブロモフェニル)-1-チロール-3-オキソ-3-(ピペリジニル)プロペン-2-イル)ベンゼンアミドを取り扱う際の実験室安全事項は何ですか?
N-(2-ブロモフェニル)-1-チロール-3-オキソ-3-(ピペリジニル)プロペン-2-イル)ベンゼンアミドは有毒で、皮膚や粘膜に刺激を与える可能性があります。...
1,3プロパンジオール,2-[2-(2アミノ-6クロロ-9Hピリミジン-9-イル)エチル-1,1,2,2-D4]-2,3-ジアセタートの市場動向や研究トレンドはどうですか?
この化合物は、新規治療薬の開発に注目されています。市場では、その有効性と安全性が評価され、研究分野では、分子生物学と医薬化学の新たな発見が期待されています。
Succinimidyl-alanyl-phenylalanyl-prolyl-phenylalanine 4-nitroanilide はどの業界で使用されていますか?
Succinimidyl-alanyl-phenylalanyl-prolyl-phenylalanine 4-nitroanilide は主に医薬品開発やポ...
メチル6-アミノ-5-クロロピリジン-2-カーボイル酸について、適用される法規ガイドラインは何ですか?
メチル6-アミノ-5-クロロピリジン-2-カーボイル酸(CAS番号: 1256794-05-4)の使用には、GHS( Globally Harmonized S...
エチル4-(シクロ Pentagonyl)アミノ-2-メチル硫化基ピリミジン-5-カルボキシレートを取り扱う際の実験室安全事項は何ですか?
取り扱いには、耐薬品性の容器を使用し、通気性の良い場所で操作することを推奨します。漏れ時は、SDS(安全データシート)を参照して適切な措置を取ること。手洗いと洗...
(S)-3-ベンZYルピペリジン塩酸塩とは何ですか?
(S)-3-ベンZYルピペリジン塩酸塩は、CAS番号1258940-00-9で表される化合物です。これは、(S)-3-苯基哌啶的盐酸盐であり、主に医薬品の原料と...
3,5-二甲基金剛胺の主な用途は何ですか?
3,5-二甲基金剛胺は、主に医薬品の原料として使用され、また抗うつ薬や抗アルツハイマー薬の開発に利用されます。さらに、化粧品や食品添加物の製造でも重要な役割を果...
ビス(4-メチル-2-ペンチル)フェニルカルボン酸エステルの代替品はありますか?
ビス(4-メチル-2-ペンチル)フェニルカルボン酸エステル (CAS番号: 1398066-13-1) の代替品には、ビス(2-エチルヘキシル)フェノールカルボ...
掲載誌
Green Chemistry

Green Chemistry provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on, but not limited to, the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998). Green chemistry is the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry is at the frontiers of this continuously-evolving interdisciplinary science and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. Submissions on all aspects of research relating to the endeavour are welcome. The journal publishes original and significant cutting-edge research that is likely to be of wide general appeal. To be published, work must present a significant advance in green chemistry. Papers must contain a comparison with existing methods and demonstrate advantages over those methods before publication can be considered. For more information please see this Editorial. Coverage includes the following, but is not limited to: Design (e.g. biomimicry, design for degradation/recycling/reduced toxicity…) Reagents & Feedstocks (e.g. renewables, CO2, solvents, auxiliary agents, waste utilization…) Synthesis (e.g. organic, inorganic, synthetic biology…) Catalysis (e.g. homogeneous, heterogeneous, enzyme, whole cell…) Process (e.g. process design, intensification, separations, recycling, efficiency…) Energy (e.g. renewable energy, fuels, photovoltaics, fuel cells, energy storage, energy carriers…) Applications (e.g. electronics, dyes, consumer products, coatings, pharmaceuticals, preservatives, building materials, chemicals for industry/agriculture/mining…) Impact (e.g. safety, metrics, LCA, sustainability, (eco)toxicology…) Green chemistry is, by definition, a continuously-evolving frontier. Therefore, the inclusion of a particular material or technology does not, of itself, guarantee that a paper is suitable for the journal. To be suitable, the novel advance should have the potential for reduced environmental impact relative to the state of the art. Green Chemistry does not normally deal with research associated with 'end-of-pipe' or remediation issues.














