Annulation of β-aryl-α-nitro-α,β-enals and 2,2-dimethyl-1,3-dioxan-5-one: a one-step assembly of nitrocyclitols. Application to a short practical synthesis of (±)-7-deoxy-2-epi-pancratistatin tetraacetate
文献情報
Juan Carlos Ortiz, Lidia Ozores, Fernando Cagide-Fagín, Ricardo Alonso
A novel, highly stereocontrolled formal [3 + 3] annulation of β-aryl-α-nitro-α,β-enals with the enamine derived from 2,2-dimethyl-1,3-dioxan-5-one and pyrrolidine afforded protected nitrocyclitols with five newly created stereocentres and constituted the key step in a short, gram-scale synthesis of a pancratistatin analogue.
関連文献
Poly(acrylate) with a tetraphenylethene pendant with aggregation-induced emission (AIE) characteristics: highly stable AIE-active polymer nanoparticles for effective detection of nitro compounds
Hui Zhou, Jiesheng Li, Ming Hui Chua, Hong Yan, Beng Zhong Tang, Jianwei Xu
DOI: 10.1039/C4PY00518J
Control over the assembly and rheology of supramolecular networks via multi-responsive double hydrophilic copolymers
Jérémy Brassinne, Charles-André Fustin, Jean-François Gohy
DOI: 10.1039/C6PY02143C
Fast conversion of terminal thiocarbonylthio groups of RAFT polymers to “clickable” thiol groups via versatile sodium azide
Yang Wu, Yanyan Zhou, Jian Zhu, Wei Zhang, Xiangqiang Pan, Zhengbiao Zhang, Xiulin Zhu
DOI: 10.1039/C4PY00732H
Synthesis of poly(ethylene glycol)-b-poly(N-(2-hydroxypropyl) methacrylamide) block copolymers with well-defined structures and their influence on in vivo circulation and biodistribution
Chengyan Dong, Jiajing Zhang, Jiyun Shi, Bing Jia, Fan Wang
DOI: 10.1039/C4PY00681J
Thermo-responsive gold/poly(vinyl alcohol)-b-poly(N-vinylcaprolactam) core–corona nanoparticles as a drug delivery system
Christophe Detrembleur, Marie Hurtgen, Antoine Debuigne, Marie-Claire De Pauw-Gillet, Stéphane Mornet, Etienne Duguet, Christine Jérôme
DOI: 10.1039/C4PY00352G
6-Oxoverdazyl radical polymers with tunable electrochemical properties
DOI: 10.1039/C4PY00829D
Nucleobase-functionalized supramolecular polymer films with tailorable properties and tunable biodegradation rates
Chih-Chia Cheng, Jyun-Jie Huang, Zhi-Sheng Liao, Shan-You Huang, Zhong Xin
DOI: 10.1039/C7PY00182G
The para-fluoro-thiol ligation in water
Parvesh Wadhwani, Rouven Müller
DOI: 10.1039/C6PY02108E
“Arm-first” approach for the synthesis of star-shaped stereoregular polymers through living coordination polymerization
Zhenghai Shi, Fang Guo, Rui Tan, Hui Niu, Tingting Li, Yang Li
DOI: 10.1039/C6PY02097F
こちらもおすすめ
「邻羟基阿托伐他汀内酯标准品」に適用される法規ガイドelinesは何ですか?
CAS番号163217-74-1の「邻羟基阿托伐他汀内酯标准品」は、GHS分類では危険物に分類されず、主にREACH規則とFDA/EPAの管理対象となります。R...
メチル(3R)-3-アミノ-2,3-ジヒドロ-1-ベンゾファンラニン-5-カルボイル酸塩塩酸塩の主な用途は何ですか?
メチル(3R)-3-アミノ-2,3-ジヒドロ-1-ベンゾファンラニン-5-カルボイル酸塩塩酸塩は、医薬品や合成化学の研究に広く用いられます。また、特定の薬物の前...
トランス-4-メチルピロリジン-3-オール塩酸塩はどのように合成されますか?
トランス-4-メチルピロリジン-3-オール塩酸塩は、4-メチルピロリジンの塩酸塩化によって合成されます。一般的な合成方法では、4-メチルピロリジンを塩酸に加えて...
硫雜環丁烷-1,1-二氧化物は安全ですか?
硫雜環丁烷-1,1-二氧化物は安全ではありません。毒性は報告されていませんが、高温下で分解し、可燃性があるため、高圧ガスは注意が必要です。密閉した容器で保管し、...
9-ヒドロキシエリプチシネ塩酸塩はどのように合成されますか?
9-ヒドロキシエリプチシネ塩酸塩は、エリプチシネから塩酸を添加することで合成されます。選択性は高いですが、収率は約70%です。
5-塩素-2-(メチルアミノ)フェニル-(2-塩素フェニル)メタン酮の物理化学的性質は何ですか?
5-塩素-2-(メチルアミノ)フェニル-(2-塩素フェニル)メタン酮のCAS番号は5621-86-3です。この化合物は白色の結晶性粉末で、分子量は415.03で...
1-[2-(4-甲氧基-苯氧基)-乙基]-哌嗪はどのように保存すればよいですか?
1-[2-(4-甲氧基-苯氧基)-乙基]-哌嗪は、直射日光を避けて暗所に、室温(15-25℃)で保管し、密閉容器に入れることで安定性を保つことができます。
2-[3-(4-甲氧基フェニル)プロピル]-4,4,5,5-四メチル-1,3,2-ドイボロロールアンの主な用途は何ですか?
2-[3-(4-甲氧基フェニル)プロピル]-4,4,5,5-四メチル-1,3,2-ドイボロロールアンは、医薬品の合成、有機合成化学、および新材料の研究で使用され...
掲載誌
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry














