An efficient and mild oxidative approach from thiols to sulfonyl derivatives with DMSO/HBr

文献情報

出版日 2023-11-01

DOI 10.1039/D3SC04945K

インパクトファクター 9.825

著者

Hongye Wang, Zhaoting Li, Rongheng Dai, Ning Jiao, Song Song

原文を見る

要旨

A mild and practical method for synthesizing sulfonyl derivatives, which have a wide range of applications in pharmaceuticals, materials, and organic synthesis, was described through the oxidative functionalization of thiols with DMSO/HBr. The simple conditions, low cost and ready availability of DMSO/HBr, as well as the versatility of the transformations, make this strategy very powerful in synthesizing a variety of sulfonyl derivatives including sulfonamides, sulfonyl fluorides, sulfonyl azides, and sulfonates. Mechanistic studies revealed that DMSO served as the terminal oxidant, and HBr acted as both a nucleophile and a redox mediator to transfer the oxygen atom.

掲載誌

Chemical Science

CiteScore: 14.4

自己引用率: 3.9%

年間論文数: 1413

Our journal has a wide-ranging scope which covers the full breadth of the chemical sciences. The research we publish contains the sorts of novel ideas, challenging questions and progressive thinking that bring undiscovered breakthroughs within reach. Your paper could focus on a single area, or cross many. It could be beyond the accepted bounds of the chemical sciences. It might address an immediate challenge, contribute to a future breakthrough or be wholly conceptual. We’re a team from every field of the chemical sciences, and know from experience that breakthroughs that drive the solutions to global challenges can come from anywhere, at any time. You could even start an entirely new area of research. Too bold? Too progressive? No such thing

An efficient and mild oxidative approach from thiols to sulfonyl derivatives with DMSO/HBr

文献情報

おすすめジャーナル

関連文献

Efficient synthesis of P-chiral biaryl phosphonates by stereoselective intramolecular cyclization

A concise total synthesis of sespenine, a structurally unusual indole terpenoid from Streptomyces

Reactivity and mechanistic insight into the cross coupling reaction between isochromans and β-keto esters through C–H bond activation under visible light irradiation

Direct isoperfluoropropylation of arenediazonium salts with hexafluoropropylene

DFT investigation of the ring contraction reaction of (η4-1,2-disilacyclohexadiene)iron tricarbonyls: a crucial intramolecular Si–Si bond activation

Tandem oxidative radical brominative addition of activated alkynes and spirocyclization: switchable synthesis of 3-bromocoumarins and 3-bromo spiro-[4,5] trienone

Metal-free oxidative hydrophosphinylation of 1,7-enynes

Front cover

Copper-catalyzed aminotrifluoromethylation of alkenes: a facile synthesis of CF3-containing lactams

Palladium-catalysed coupling reaction of aminals with N-sulfonyl hydrazones to give allylic sulfones

こちらもおすすめ

1-{3-[5-(エチルカルボンイル)-2,4-ジメチル-1H-ピロロール-3-基]プロパニル}ピペリジン-4-カルボン酸について、適用される法規ガイドラインは何ですか？

2,2-二氟-1,3-ベンゾジオキサン-5-カルボキシlic酸とは何ですか？

8-氯-4-色原酮の代替品はありますか？

エチル6,6-ジメチル-4,5,6,7-テトラヒドロ-1H-インドアゼー-3-カルボキシレートとは何ですか？

4-叔丁基-6-氯-嘧啶に適用される法規ガイドラインは何ですか？

維库溴铵杂质Bはどのように合成されますか？

2-(4-氟苄基)-吡咯烷の物理化学的性質は何ですか？

3-喹啉甲醛（2-チロール-8-エチル）は安全ですか？

エチル3-(ヒドロキシメチル)-1H-ピロール-2-カルボキシレートはどのように保存すればよいですか？

哌拉西林杂质Dは安全ですか？

掲載誌

Chemical Science

おすすめ化合物

Danthron (1,8-Dihydroxyanthraquinone)

Glycol salicylate

3-Bromophenylboronic acid

Methyl 4-chloro-2-pyridinecarboxylate

3-[(4-Nitrobenzyl)oxy]-3-oxopropanoic Acid

おすすめサプライヤー