Copper-catalyzed aminotrifluoromethylation of alkenes: a facile synthesis of CF3-containing lactams

文献情報

出版日 2015-12-10

DOI 10.1039/C5QO00353A

インパクトファクター 5.281

著者

Kun Shen, Qiu Wang

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要旨

Copper-catalyzed aminotrifluoromethylation of alkenes using amides as nucleophiles has been developed. It provides a rapid and efficient access to a variety of CF3-containing lactams. The reaction proceeds under mild conditions with a good scope and functional group tolerance, offering a valuable method to prepare CF3-containing lactams that are of great potential in pharmaceuticals and agrochemicals.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Copper-catalyzed aminotrifluoromethylation of alkenes: a facile synthesis of CF3-containing lactams

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