Two-step, high-yielding total synthesis of antibiotic pyrones

文献情報

出版日 2023-12-14

DOI 10.1039/D3OB01923C

インパクトファクター 3.876

著者

Akram Hussain, Sunitha Katta, Dhevalapally B. Ramachary

原文を見る

要旨

A simple two-step dialkylation protocol was developed to synthesize biologically active antibiotics photopyrones, pseudopyronines, and violapyrones from bio-renewable triacetate lactone in excellent yields. These pyrones are functionally modified into another set of pyrone natural products by a single O-methylation reaction. The high-yielding gram scale synthesis of four natural products [pseudopyronine A, photopyrone A, pseudopyronine B and photopyrone C] demonstrated the viability for industrial applications.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Two-step, high-yielding total synthesis of antibiotic pyrones

文献情報

おすすめジャーナル

関連文献

Crystal size-controlled growth of bismuth vanadate for highly efficient solar water oxidation

Correction: Using high-throughput virtual screening to explore the optoelectronic property space of organic dyes; finding diketopyrrolopyrrole dyes for dye-sensitized water splitting and solar cells

Tungsten oxide-coated copper gallium selenide sustains long-term solar hydrogen evolution

The controlled synthesis of V-doped MoS2-NixSy hollow nanospheres and their electrocatalytic performance in hydrogen evolution reaction

Pt atoms on doped carbon nanosheets with ultrahigh N content as a superior bifunctional catalyst for hydrogen evolution/oxidation

Ultrathin MoS2 wrapped N-doped carbon-coated cobalt nanospheres for OER applications

Alternate cycles of CO2 storage and in situ hydrogenation to CH4 on Ni–Na2CO3/Al2O3: influence of promoter addition and calcination temperature

Enhanced oxygen evolution catalytic activity of NiS2 by coupling with ferrous phosphite and phosphide

Morphologically controlled rapid fabrication of rhodium sulfide (Rh2S3) thin films for superior and robust hydrogen evolution reaction

Analysis of manufacturing cost and market niches for Cu2ZnSnS4 (CZTS) solar cells

こちらもおすすめ

5-苄基四氢吡咯并[3,4-c]吡咯-1,3[2H,3ah]-二酮の主な用途は何ですか？

唾液酸路易ス Aを取り扱う際の実験室安全事項は何ですか？

タルトブチル ((1-(2-クロロアセチル)ピペリジン-4-イルメチル)カーバamatはどの業界で使用されていますか？

3-烯丙基-2-羟基苯甲醛の物理化学的性質は何ですか？

乳清酸 Potassium Orotateとは何ですか？

4-甲基苯磺酸异丙酯はどの業界で使用されていますか？

6-(3- Florobenzen)-N-[1-(2,2,2- Trifluoroethyl)-4-Piperidinyl]-3-Pyridinycarboxamideはどの業界で使用されていますか？

左西孟旦はどのように合成されますか？

3-乙氧基哌啶盐酸盐に適用される法規ガイドラインは何ですか？

Diethyl (hydroxymethyl)phosphonateの主な用途は何ですか？

掲載誌

Organic & Biomolecular Chemistry

おすすめ化合物

Ethyl 5,6-difluoro-1H-indole-2-carboxylate

Ethyl 5-[({[(2-methyl-2-propanyl)oxy]carbonyl}amino)methyl]-1,2-oxazole-3-carboxylate

4-{2-[(9H-Fluoren-9-ylmethoxy)carbonyl]hydrazino}benzoic acid

5-Phenyl-1,3-benzoxazole-2(3H)-thione

4-Bromo-N-(4-methoxybenzyl)benzenesulfonamide

おすすめサプライヤー