Facile access to 5H-thiazolo[2′,3′:2,3]imidazo[4,5-b]indole derivatives by two-fold Cu-catalysed C–N coupling reactions

文献情報

出版日 2023-10-16

DOI 10.1039/D3OB01515G

インパクトファクター 3.876

著者

Bao Chi Quang Nguyen, Ban Van Phuc, Tien Dat Dang Van, Chu Mai Trang, Quang Thi Kim Anh, Dang Van Do, Hien Nguyen, Tuan Thanh Dang

原文を見る

要旨

In four simple steps, a series of 5H-thiazolo[2′,3′:2,3]imidazo[4,5-b]indole and 11H-benzo[4′,5′]thiazolo[2′,3′:2,3]imidazo[4,5-b]indole derivatives were prepared with high yields. The key step in this procedure was demonstrated to be two-fold Cu-catalysed C–N coupling reactions of 5-bromo-6-(2-bromophenyl)imidazo[2,1-b]thiazole and 3-bromo-2-(2-bromophenyl)benzo[d]imidazo[2,1-b]thiazole with various amines.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.