Rhodium(iii)-catalyzed annulation of 3-arylquinazolinones with alkynes via double C–H activation: an efficient route for quinolino[2,1-b]quinazolinones

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出版日 2021-09-27

DOI 10.1039/D1QO01186C

インパクトファクター 5.281

著者

Jian Huang, Wei Chen, Jiazhi Liang, Qin Yang, Zhihong Deng, Zhibin Song, Yiyuan Peng

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要旨

An effective method for the synthesis of quinolino[2,1-b]quinazolinones has been described. The O-directing Rh(III)-catalyzed C–H activation of 3-arylquinazolinones and alkynes gave the corresponding polyaryl substituted quinolino[2,1-b]quinazolinones in good to excellent yields. The results of competition and isotope-labeling experiments support the proposed double C–H activation mechanism. The synthesized quinolino[2,1-b]quinazolinones exhibit a blue-colored emission and large Stokes shifts (67–123 nm) as well as emit visible fluorescence with good fluorescence quantum yields in the solid state.

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Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Rhodium(iii)-catalyzed annulation of 3-arylquinazolinones with alkynes via double C–H activation: an efficient route for quinolino[2,1-b]quinazolinones

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Contents list

Recent developments in palladium-catalyzed C–S bond formation

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