Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles

文献情報

出版日 2021-05-07

DOI 10.1039/D1QO00220A

インパクトファクター 5.281

著者

Yongchao Wang, Angel A. Cobo, Annaliese K. Franz

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要旨

Asymmetric catalytic multicomponent cascade reactions have become indispensable tools for enantioselective construction of spirooxindoles. In recent years, a number of successful strategies have been developed for the synthesis of enantioenriched spirooxindoles in high yield with excellent stereo- and regioselectivity. This review summarizes the recent advances on enantioselective construction of spirooxindoles including spiro[N-heterocycle-oxindoles], spiro[cycloalkane-oxindoles] and spiro[O-heterocycle-oxindoles] catalyzed by chiral phosphoric acids, amines, and bifunctional thiourea/squaramides.

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掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles

文献情報

おすすめジャーナル

関連文献

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Back cover

Xanthine-based photoaffinity probes allow assessment of ligand engagement by TRPC5 channels

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Chemical methods for protein site-specific ubiquitination

Enabling the next steps in cancer immunotherapy: from antibody-based bispecifics to multispecifics, with an evolving role for bioconjugation chemistry

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