Aqueous ROPISA of α-amino acid N-carboxyanhydrides: polypeptide block secondary structure controls nanoparticle shape anisotropy

文献情報

出版日 2021-09-21

DOI 10.1039/D1PY00995H

インパクトファクター 5.582

著者

Pedro Salas-Ambrosio, Ségolène Antoine, Emmanuel Ibarboure, Olivier Sandre, Mark W. Grinstaff, Sébastien Lecommandoux, Colin Bonduelle

原文を見る

要旨

Polymerization-induced self-assembly (PISA) is an efficient one-step process to obtain nanomaterials. In this work, aqueous ring-opening polymerization induced self-assembly (ROPISA) of α-amino acid N-carboxyanhydride (NCA) affords controllable well-defined nanoassemblies. ROPISA with the PEG5 kDa-NH2 macroinitiator and either the benzyl-L-glutamate NCA (BLGNCA) or L-leucine NCA (LeuNCA) monomer yields amphiphilic block copolymers, with different polypeptide molar masses, which spontaneously form nanostructures. In contrast to the previous PISA process where the hydrophobic to hydrophilic ratio was the main parameter defining nanomaterial morphology, the secondary structure of the polypeptides is the main driving force to stabilize the anisotropic rod-like nanostructures with this ROPISA process.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Aqueous ROPISA of α-amino acid N-carboxyanhydrides: polypeptide block secondary structure controls nanoparticle shape anisotropy

文献情報

おすすめジャーナル

関連文献

Development of a high throughput (HT) Raman spectroscopy method for rapid screening of liquid blood plasma from prostate cancer patients

Determination of the transfer function of an atmospheric pressure drift tube ion mobility spectrometer for nanoparticle measurements

Recent advances in boronic acid-based optical chemosensors

Monitoring the biochemical alterations in hypertension affected salivary gland tissues using Fourier transform infrared hyperspectral imaging

Front cover

Back cover

Rapid single-cell detection and identification of pathogens by using surface-enhanced Raman spectroscopy

Ultra-filtration of human serum for improved quantitative analysis of low molecular weight biomarkers using ATR-IR spectroscopy

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

SIproc: an open-source biomedical data processing platform for large hyperspectral images

こちらもおすすめ

3-イチチルビフェニルはどのように合成されますか？

8-溴-5-三氟甲基喹啉はどのように合成されますか？

ジメチル4-(4,4,5,5-テトラメチル-1,3,2-ドioxaborolan-2-基)-2,6-ピリジンジカルボイル酸フェニルアミニドの代替品はありますか？

N-(3,5-ヘキサクロロ-4-ピリドインイル)-8-メチオキシ-5-キノリンカーボン酸の市場動向や研究トレンドはどのようなものでしょうか？

イソステアロイルグリセリルは安全ですか？

1-(二苯甲基)-3,3-二氟-氮杂环丁烷の市場動向や研究トレンドはどうですか？

3-チオフェンスチオールの物理化学的性質は何ですか？

2-Methyl-2-propanyl (2S)-2-(aminomethyl)-1-piperidinecarboxylateは安全ですか？

CAS番号1316822-90-8の化合物は安全ですか？

Tert-butyl 2-(2-羟基乙基)哌嗪-1-羧酸はどのように保存すればよいですか？

掲載誌

Polymer Chemistry

おすすめ化合物

N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-methionylglycine

2-(4,4-Difluorobutyl)-1H-isoindole-1,3(2H)-dione

Fenofibrate-d6

1-Isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-beta-carboline

Benzyl 6-oxo-3,6-dihydro-1(2H)-pyridinecarboxylate

おすすめサプライヤー