In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

文献情報

出版日 2018-07-30

DOI 10.1039/C8AN00913A

インパクトファクター 4.616

著者

Oliver Jonas, Jeon Woong Kang, Surya P. Singh, Alex Lammers, Freddy T. Nguyen, Ramachandra R. Dasari, Peter T. C. So, Robert Langer

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要旨

We describe a label-free approach based on Raman spectroscopy, to study drug-induced apoptosis in vivo. Spectral-shifts at wavenumbers associated with DNA, proteins, lipids, and collagen have been identified on breast and melanoma tumor tissues. These findings may enable a new analytical method for rapid readout of drug-therapy with miniaturized probes.

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Analyst

CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

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