Sequence-controlled and sequence-defined polypeptoids via the Ugi reaction: synthesis and sequence-driven properties

文献情報

出版日 2021-07-19

DOI 10.1039/D1PY00658D

インパクトファクター 5.582

著者

Yinuo Zhu, Youhua Tao

原文を見る

要旨

Polypeptoids are peptidomimetic polymers, and their origin can be traced back to the early 1990s. The facile synthesis of sequence-controlled and sequence-defined polypeptoids still faces many challenges. Very recently, the Ugi reaction has been introduced into polypeptoid chemistry. In this mini review, the recent progress in the application of the Ugi reaction for the synthesis of sequence-controlled polypeptoids is summarized. The influence of the sequence structure on polypeptoid properties is presented. Moreover, the future development of the Ugi reaction for the synthesis of sequence-controlled and sequence-defined polypeptoids is discussed.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Sequence-controlled and sequence-defined polypeptoids via the Ugi reaction: synthesis and sequence-driven properties

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