Transition-metal-free direct C-3 alkylation of quinoxalin-2(1H)-ones with ethers

文献情報

出版日 2018-08-24

DOI 10.1039/C8QO00731D

インパクトファクター 5.281

著者

Jinwei Yuan, Junhao Fu, Jihong Yin, Zhenhua Dong, Yongmei Xiao, Pu Mao

原文を見る

要旨

A convenient and efficient transition-metal-free protocol for the synthesis of 3-alkyl quinoxalin-2(1H)-ones from the radical reaction of quinoxalin-2(1H)-ones with ethers was developed with moderate to good yields. The methodology shows broad substrate scope, excellent functional group tolerance, high atom economy and high efficiency, thus enabling the preparation of diverse potentially valuable 3-alkyl quinoxalin-2(1H)-one derivatives.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Transition-metal-free direct C-3 alkylation of quinoxalin-2(1H)-ones with ethers

文献情報

おすすめジャーナル

関連文献

Highly selective and sensitive assay for paclitaxel accumulation by tumor cells based on selective solid phase extraction and micro-flow liquid chromatography coupled to mass spectrometry

Broadband terahertz time-domain spectroscopy of drugs-of-abuse and the use of principal component analysis

Recent advances in immobilization methods of antibodies on solid supports

Contents and Chemical Technology

Back cover

Ratiometric photoacoustic sensing of pH using a “sonophore”

Back cover

Demonstration of sandwich and competitive modulated supraparticle fluoroimmunoassay applied to cardiac proteinbiomarkermyoglobin

Front cover

Turn-on fluorescent cyanide sensor based on copper ion-modified CdTe quantum dots

こちらもおすすめ

4'-ブロモビフェニル-3-メトークシーディ.ActionBarはどのように保存すればよいですか？

間甲苯乙腈とは何ですか？

2-異丙基フェニルヒドラジン塩酸塩とは何ですか？

5-(4-クロロフェニル)-4H-1,2,4-三氮唑-3-アミンを取り扱う際の実験室安全事項は何ですか？

去甲基雷贝拉唑硫醚はどのように合成されますか？

2-ブロモ-5-フロロ-N-(2-フェノールメチル)ベンゼンウレアは安全ですか？

対甲苯磺酸酯-四聚乙二醇-四氢吡喃醚の物理化学的性質は何ですか？

2-(3-(二氟甲基)-4-氟苯基)-4,4,5,5-四甲基-1,3,2-二噁硼戊環はどのように保存すればよいですか？

6-アミノ-5-クロロ-2-シクロプロピルピリミジンカルボン酸の代替品はありますか？

5-クロロベンゾ[1,3]二オキセイン-4-アミンに適用される法規ガイドラインは何ですか？

掲載誌

Organic Chemistry Frontiers

おすすめ化合物

(1S)-1,5-Anhydro-2-O-alpha-L-arabinopyranosyl-1-[5-hydroxy-7-({6-O-[3-(4-hydroxy-3-methoxyphenyl)propanoyl]-beta-D-glucopyranosyl}oxy)-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl]-D-glucitol

(9Z,21S,27S,38Z)-24-Hydroxy-24-oxido-18,30-dioxo-19,23,25,29-tetraoxa-24lambda~5~-phosphaheptatetraconta-9,38-diene-21,27-diyl (9Z,9'Z)bis(-9-octadecenoate) ammoniate (1:1)

2-Hydroxy-5-iodo-4-methylbenzoic acid

{3-[Bis(4-hydroxyphenyl)methyl]-1-[2-(dimethylamino)ethyl]-1H-indol-2-yl}[4-(2-chlorophenyl)-1-piperazinyl]methanone

1-(5-Bromo-2-fluorophenyl)-2,2,2-trifluoroethanol

おすすめサプライヤー