Copper-catalyzed synthesis of 2,2,2-trifluoroethyl selenoethers and their insecticidal activities

文献情報

出版日 2018-11-16

DOI 10.1039/C8OB02647E

インパクトファクター 3.876

著者

Jingnan Dong, Zhengyu Li, Zhiqiang Weng

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要旨

A simple and efficient protocol for the copper-catalyzed synthesis of aryl or alkyl 2,2,2-trifluoroethyl selenoethers has been developed. This reaction proceeded smoothly in the presence of CuI/phen as the catalyst, with elemental selenium, 1,1,1-trifluoro-2-iodoethane, and NaBH4 as reagents in DMF with a broad scope of functionalized (hetero)aryl or alkyl halides. Different functional groups were tolerated and moderate to excellent yields of 2,2,2-trifluoroethyl selenoethers were obtained. Some of the synthesized compounds exhibited promising insecticidal activities.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

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