Controlling ionic conductivity through transprotein electropores in human aquaporin 4: a non-equilibrium molecular-dynamics study
文献情報
Mario Bernardi, Paolo Marracino, Micaela Liberti, José-Antonio Gárate, Christian J. Burnham, Francesca Apollonio, Niall J. English
Electroporation is a matter of intensive ongoing research interest, and a much-neglected topic in trans-membrane proteins, particularly in view of such promising potential applications in medicine and biotechnology. In particular, selected such novel and exciting applications are predicated on controlling ionic conductivity through electro-pores. Here, we scrutinise the mechanisms of ions’ electric conductivity, by means of structural rearrangements, through quasi-stable electro-pores through human-AQP4 as a well-representative prototype of trans-membrane ionic conduction, achieving exquisite control over ionic permeability manipulated by the application of intense static electric fields.
おすすめジャーナル

Acta Metallurgica Sinica-English Letters

Journal of Asian Natural Products Research

Heteroatom Chemistry

Journal of the Indian Institute of Science

Atomization and Sprays

Medicinal Chemistry Research

Topics in Catalysis

Herald of the Russian Academy of Sciences

Journal of Chemical Sciences

Chinese Journal of Chemistry
関連文献
Two-dimensional ternary pentagonal BCX (X = P, As, and Sb): promising photocatalyst semiconductors for water splitting with strong piezoelectricity
Luqi Liu, Xuxin Kang
DOI: 10.1039/D3CP04866G
Degradation analysis of inverted PM6 (PBDB-T-2F):Y7 (BTP-4CI) solar cells with PDINO and MoO3 as the ETL/HTL
Angel Sacramento, José L. Abad, Magaly Ramírez-Como, Victor S. Balderrama, Magali Estrada
DOI: 10.1039/D3SE00977G
Highly efficient hydrogen production and selective CO2 reduction by the C3N5 photocatalyst using only visible light
Kosei Ito, Kei Noda
DOI: 10.1039/D3CP04431A
Direct thermodynamic characterization of solid-state reactions by isothermal calorimetry
Marija Cvetnić, Robert Šplajt, Edi Topić, Mirta Rubčić, Nikola Bregović
DOI: 10.1039/D3CP03933A
Development and test of highly accurate endpoint free energy methods. 3: partition coefficient prediction using a Poisson–Boltzmann method combined with a solvent accessible surface area model for SAMPL challenges
Taoyu Niu, Xibing He, Fengyang Han, Luxuan Wang, Junmei Wang
DOI: 10.1039/D3CP04174C
Simulation of exciton spectra in disordered supramolecular polymers: exciton localization in cisoid indolenine squaraine hexamers
David Fischermeier, Arthur Turkin, Joshua Selby, Roland Mitrić
DOI: 10.1039/D3CP04557A
Selective regression models for the rapid upgrading of raw sugar into 5-HMF bio-fuel additive under a sustainable/reusable system
Panya Maneechakr, Irwan Kurnia, Asep Bayu, Obie Farobie, Chanatip Samart, Suwadee Kongparakul, Guoqing Guan, Surachai Karnjanakom
DOI: 10.1039/D3SE00788J
Group 13 five- and six-membered rings with rare 2π aromaticity
Yutong Huo, Xiaojiao Gu, Xinde Li, Peng Jin
DOI: 10.1039/D3CP04159J
Tailoring flavin-based photosensitizers for efficient photooxidative coupling of benzylic amines
Huimin Guo, Yang Qiu, Siyu Liu, Xiangyu Zhang, Jianzhang Zhao
DOI: 10.1039/D3CP04579J
Water dynamics in eutectic solutions of sodium chloride and magnesium sulfate: implications for life in Europa's subsurface ocean and ice shell
Daniel Sieme
DOI: 10.1039/D3CP03455K
こちらもおすすめ
N,N-二乙基-4-ブロモナフサルレン-1-カルボニルアミドはどのように合成されますか?
N,N-二乙基-4-ブロモナフサルレン-1-カルボニルアミドは、4-ブロモナフサルビンとN,N-ジエチルアミド基を有する反応物を用いて合成されます。触媒の使用は...
大黄酚-8-O-葡萄糖苷の市場動向や研究トレンドはどうですか?
大黄酚-8-O-葡萄糖苷の市場は、医薬品、機能食品、研究化学物質としての需要が高まっています。特に、その抗炎症作用や抗ウイルス作用に関する研究が増えています。価...
アトラキュリウム不純物5塩酸塩の物理化学的性質は何ですか?
アトラキュリウム不純物5塩酸塩のCAS番号は2048273-58-9です。この化合物は結晶性であり、分子量は約435.4 g/molです。水に溶けやすく、反応性...
2-イソブチルシクロヘキサン酮とは何ですか?
2-イソブチルシクロヘキサン酮は、CAS番号39207-65-3の化合物で、化学式はC11H20Oです。この化合物は、有機合成化学において重要な原料として使用さ...
2-溴-6-甲基烟酸を取り扱う際の実験室安全事項は何ですか?
この化合物は毒性と刺激性があります。密閉されたドラフトチャンバー内で処理し、PPE(ゴーグル、手袋)を使用してください。漏洩時は即座に通気し、適切な漏洩処理材を...
6-アミノニコニタルデオキシド塩化水和物の物理化学的性質は何ですか?
6-アミノニコニタルデオキシド塩化水和物のCAS番号は1588441-31-9です。この化合物は結晶性粉末で、分子量は220.63 g/molです。水に溶けやす...
塩酸中毒藜碱はどのように合成されますか?
塩酸中毒藜碱は、ピペリジンとピリジンの反応により合成されます。具体的には、ピペリジンとピリジンを反応させ、塩基触媒を使用してピペリジン環内 enters 3-ピ...
Methyl 4-(6-formyl-2-pyridinyl)benzoateに適用される法規ガイドラインは何ですか?
この化合物はCAS番号834884-81-0で、GHS分類では高毒性の危険性を持つと見なされます。REACH規則では登録が求められ、FDA/EPAでは環境、健康...
1-エチynyル-3-(三氟甲氧基)ベンゼンについて「に適用される法規ガイドラインは何ですか」
CAS番号 866683-57-0の1-エチynyル-3-(三氟甲氧基)ベンゼンは、GHS分類では易燃性化学品が該当し、REACH規則では特定の危険性を評価する...
メチル2-ブロモイソニコネートの代替品はありますか?
メチル2-ブロモイソニコネートの代替品には、メチルイソニコネートや他のブロモ化合物が含まれます。これらの代替物は、特定の用途に応じて選択されます。
掲載誌
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.
![(2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid structure (2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid structure](https://static.chemtradehub.com/structs/102/102410-65-1-4aa7.webp)



