Synthesis and bioconjugation of first alkynylated poly(dithieno[3,2-b:2′,3′-d]pyrrole)s

文献情報

出版日 2017-11-06

DOI 10.1039/C7PY01528C

インパクトファクター 5.582

著者

Sylvia Schmid, Jasmina Gačanin, Peter Bäuerle

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要旨

First synthesis of an alkynylated dithieno[3,2-b:2′,3′-d]pyrrole (DTP) monomer was developed, which allows electrochemical polymerization on platinum and indium tin oxide (ITO) electrodes. The obtained DTP-based polymer (pDTP) was successfully post-modified with redox active and biological entities via bio-orthogonal 1,3-dipolar cycloaddition reactions and [2 + 2]-cycloaddition. In vitro experiments with A549-human lung carcinoma cells evidenced the general biocompatibility of the compositionally tuneable pDTP-coated electrodes.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

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Synthesis and bioconjugation of first alkynylated poly(dithieno[3,2-b:2′,3′-d]pyrrole)s

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