Facile thiolation of hydroxyl functional polymers

文献情報

出版日 2017-07-18

DOI 10.1039/C7PY01097D

インパクトファクター 5.582

著者

O. C. J. Andrén, M. Malkoch

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要旨

Sulfur is an important component in many biological systems. In the hands of an organic chemist it can provide an ample handle for a myriad of robust reactions including thiol–ene click chemistry. However, in polymer chemistry the thiol functionality is rarely attributed to the macromolecule due to unatainable synthetic protocols. Herein, we provide a simple and robust strategy to produce thiol-functional polymers. The chemistry capitalizes on an unsymmetrical disulfide that straightforwardly converts hydroxyl functional polymers to their thiolated counterpart. Finally, PEG hydrogels, using both thiol–ene and Michael addition, is used to showcase the possibilities presented by thiol functional polymers.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Facile thiolation of hydroxyl functional polymers

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