High-resolution microstrip NMR detectors for subnanoliter samples
文献情報
Ying Chen, Hardeep S. Mehta, Mark C. Butler, Eric D. Walter, Patrick N. Reardon, Ryan S. Renslow, Karl T. Mueller, Nancy M. Washton
We present the numerical optimization and experimental characterization of two microstrip-based nuclear magnetic resonance (NMR) detectors. The first detector, introduced in our previous work, was a flat wire detector with a strip resting on a substrate, and the second detector was created by adding a ground plane on top of the strip conductor, separated by a sample-carrying capillary and a thin layer of insulator. The dimensional parameters of the detectors were optimized using numerical simulations with regards to radio frequency (RF) sensitivity and homogeneity, with particular attention given to the effect of the ground plane. The influence of copper surface finish and substrate surface on the spectral resolution was investigated, and a resolution of 0.8–1.5 Hz was obtained on 1 nL deionized water depending on sample positioning. For 0.13 nmol sucrose (0.2 M in 0.63 nL H2O) encapsulated between two Fluorinert plugs, high RF homogeneity (A810°/A90° = 70–80%) and high sensitivity (expressed in the limit of detection nLODm = 0.73–1.21 nmol s1/2) were achieved, allowing for high-performance 2D NMR spectroscopy of subnanoliter samples.
おすすめジャーナル

Nature Reviews Drug Discovery

Foundations of Chemistry

Current Pharmaceutical Biotechnology

Mini-Reviews in Medicinal Chemistry

Environmental Toxicology and Pharmacology

Contact Lens & Anterior Eye

Angewandte Chemie International Edition

Journal of Enzyme inhibition and Medicinal Chemistry

Journal of Medical Biochemistry

Molecules
関連文献
Recent advances in ambient electrochemical methane conversion to oxygenates using metal oxide electrocatalysts
Fengli Liu, Yong Yan, Ge Chen, Dong Wang
DOI: 10.1039/D3GC03513A
Electrochemically exfoliated covalent organic frameworks for improved photocatalytic hydrogen evolution
Ruijuan Zhang, Pengda Zhai, Xinying Liu
DOI: 10.1039/D3TA06312G
Direct measurement of the hydrogen adsorption entropy on shape-controlled Pt nanoparticles using electrochemical microcalorimetry
Luis E. Botello, José Solla-Gullón, Víctor Climent, Juan M. Feliu, Rolf Schuster
DOI: 10.1039/D3TA04937J
rGO coated cotton fabric and thermoelectric module arrays for efficient solar desalination and electricity generation
Amrit Kumar Thakur, Wayesh Qarony, Md Shamim Ahamed, Y. Ma
DOI: 10.1039/D3TA04715F
Perylene-diimide for organic solar cells: current scenario and prospects in molecular geometric, functionalization, and optoelectronic properties
Pachaiyappan Murugan, Ezhakudiayan Ravindran, Vajjiram Sangeetha, Shi-Yong Liu
DOI: 10.1039/D3TA04925F
Switching the adsorption sites of PMS on SrCoO2.52 to enhance catalytic performance
Jiahong He, Qiang Xu, Bin Xiang
DOI: 10.1039/D3TA06102G
Solvation structure regulation of an organic small molecule additive for dendrite-free aqueous zinc-ion batteries
Xiaomin Li, Jinwei Miao, Fulong Hu, Kang Yan, Lin Song, Huiqing Fan, Longtao Ma, Weijia Wang
DOI: 10.1039/D3TA05814J
Rational design of a carbon/potassium poly(heptazine imide) heterojunction for enhanced photocatalytic H2 and H2O2 evolution
Christian Mark Pelicano, Jiaxin Li, María Cabrero-Antonino, Ingrid F. Silva, Lu Peng, Nadezda V. Tarakina, Sergio Navalón, Hermenegildo García, Markus Antonietti
DOI: 10.1039/D3TA05701A
Fluorinated carbon nitride with a hierarchical porous structure ameliorating PEO for high-voltage, high-rate solid lithium metal batteries
Shuohan Liu, Jieqing Shen, Zhikai Wang, Wensheng Tian, Xiujun Han, Zhixin Chen, Hui Pan, Lei Wang, Dongyu Bian, Shenmin Zhu
DOI: 10.1039/D3TA05495K
Optimizing dense particles for efficient thermochemical fuel generation through a unified particle-level model
Shuai Deng
DOI: 10.1039/D3TA05437C
こちらもおすすめ
噻奈普汀乙酯の物理化学的性質は何ですか?
CAS番号66981-77-9の噻奈普汀乙酯は、結晶性白色粉末であり、分子量は476.9 g/molです。この化合物は水に溶けにくく、一般的には有機溶媒で溶解し...
アミピシリン不純物Fとは何ですか?
アミピシリン不純物Fは、CAS番号124774-48-7の化合物です。これは、抗生物質アミピシリンの生産過程で生成される不純物の一つであり、(4S)-2-({[...
イリジウム(I)ヘキサフルオロフォスファートの代替品はありますか?
イリジウム(I)ヘキサフルオロフォスファートの代替品として、他の有機金属化合物や非有機金属化合物が使用されることがあります。具体的には、ダイゾニウム塩や他の金属...
含有3-(苯氧基甲基)苯硼酸频那醇酯の廃棄物はどのように処理すべきですか?
含有3-(苯氧基甲基)苯硼酸频那醇酯の廃棄物は、安全な方法で処理する必要があります。まず、廃棄物を適切な容器に収集し、避けて保管します。次に、専門の廃棄処理業者...
2-甲基辛-1-醇を取り扱う際の実験室安全事項は何ですか?
取り扱う際は、密閉のゴーグルと手袋を着用することが推奨されます。ドラフトチャンバーを使用し、漏洩時には速やかに取り扱いを中止し、適切な排気設備を使用してください...
3α-アセトキノイドコレステロールエステルはどのように保存すればよいですか?
3α-アセトキノイドコレステロールエステルは、常温から低温(0-5℃)の暗所で保存し、密閉容器に入れることで安定性を保つことが推奨されます。また、湿気や酸素から...
2-ぶンジロキシ-4-(トリフルオロメチル)フェノルビノン酸の主な用途は何ですか?
2-ぶンジロキシ-4-(トリフルオロメチル)フェノルビノン酸は、化学合成の触媒としての使用や、医薬品の合成材料としての役割があります。また、特定の合成路線で使用...
(2S,3R)-2-氨基-3-甲基丁二酸はどのように合成されますか?
(2S,3R)-2-氨基-3-甲基丁二酸は、2-ヒドロキシ-3-メチル丁酸とアミノ化反応を行うことで合成されます。触媒としてジクロロメタンが使用され、選択性と収...
1-Benzyl-2-phenyl-1H-imidazoleはどのように保存すればよいですか?
この化合物は常温で避けてください。直射日光を避け、密閉容器で保存し、湿気を防水の容器に入れて保管してください。
掲載誌
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.




![4,4'-[2,5-Biphenyldiylbis(oxy)]dianiline structure 4,4'-[2,5-Biphenyldiylbis(oxy)]dianiline structure](https://static.chemtradehub.com/structs/941/94148-67-1-24c6.webp)