Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells

文献情報

出版日 2012-10-04

DOI 10.1039/C2AN35877H

インパクトファクター 4.616

著者

Michael D. Scott, Rinku Dutta, Manas K. Haldar, Anil Wagh, Thomas R. Gustad, Benedict Law, Daniel L. Friesner, Sanku Mallik

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要旨

Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.

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CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells

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