Functionalized nanoscale through microscale polypeptide stabilized emulsions for display of biomolecules

文献情報

出版日 2011-03-15

DOI 10.1039/C1PY00045D

インパクトファクター 5.582

著者

Jarrod A. Hanson

原文を見る

要旨

We have prepared stable nano- and microscale emulsion droplets using block copolypeptide surfactants that have been functionalized with biotin. We have varied the biotin density on the droplet surfaces by mixing biotinylated with non-biotinylated surfactants, and used these to optimize the level of biotinylation for binding of NeutrAvidin. Using fluorescence microscopy and dynamic light scattering we have verified specific binding of NeutrAvidin to the biotinylated droplets and developed conditions for specific binding of biotinylated ligands to the NeutrAvidin coated droplets. These experiments outline a process for preparation of a soft, nano- through microscale sized droplet platform capable of specifically conjugating and displaying biotinylated molecules.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Functionalized nanoscale through microscale polypeptide stabilized emulsions for display of biomolecules

文献情報

おすすめジャーナル

関連文献

Understanding charge storage in Nb2CTx MXene as an anode material for lithium ion batteries

Adenine ultrafast photorelaxation via electron-driven proton transfer

Kinetic and thermodynamic stability comparison for the fibrillar form of small amyloid-β(1–42) oligomers using scaled molecular dynamics

Generation, contraction, and polarisation of Gaussian basis sets for atomic and molecular calculations using the generator coordinate method with polynomial discretisation: atoms from Na through Cl

Oscillatory dynamics during the methanol electrooxidation reaction on Pt(111)

Large Rashba splitting, carrier mobility, and valley polarization in a 1T-SnS2/MoTe2 heterostructure

From water-rich to oil-rich gelled non-toxic microemulsions

Cation enrichment in the ion atmosphere is promoted by local hydration of DNA

Evidence of gas-phase pyranose-to-furanose isomerization in protonated peptidoglycans

Unravelling the nature of a toluene–fumaronitrile complex

こちらもおすすめ

間溴苯甲酰腈の市場動向や研究トレンドはどうですか？

去磺基萝卜硫苷とは何ですか？

Methyl 2-amino-5-(trifluoromethyl)benzoateに適用される法規ガイドラインは何ですか？

3-ブロモ-1,3,4,5-四水化-2H-1-ベンザアゼピン-2-オンは安全ですか？

三氟甲基ピリジン-2-甲アミン塩酸塩は安全ですか？

1-エチル-4-(4-硝基フェニル)ピペリジンは安全ですか？

1,1-ジメトキシプロパン-2-オンは安全ですか？

コバルト(II) 3,3'-{[(1S,2S)-1,2-ジメチルフENCYCLICALE-1,2-エチエンジイル]ビス[ニトロリルメチルイリデン]}ビス[4-オキソ-2-ペンテン-2-olate]について「に適用される法規ガイドラインは何ですか？

「カーバミル酸, N-[8-[[2-[[2-(2,6-ジオキソ-3-ピペリジニル)-2,3-ジオキソ-1,3-ジヒドロ-1H-イソイソインドール-4-イルオキシ]アセチル]アミノ]オクチル]-1,1-ジメチレチルエステル」はどのように保存すればよいですか？

FMoc-D-4-Aph(tBu-CbM)-OHはどのように保存すればよいですか？

掲載誌

Polymer Chemistry

おすすめ化合物

3,3-Dimethoxy-2-butanone

(2E)-3-(3-Cyanophenyl)acrylic acid

2-Ethoxy-3,4-dihydro-2H-pyran

1-Bromo-2-chloro-4-methoxybenzene

1,1'-[(E)-1,2-Ethenediyl]bis(4-bromobenzene)

おすすめサプライヤー