Polymersomes enhance the immunogenicity of influenza subunit vaccine

文献情報

出版日 2011-03-29

DOI 10.1039/C1PY00010A

インパクトファクター 5.582

著者

Christophe Barnier Quer, Hana Robson Marsden, Stefan Romeijn, Harshal Zope, Alexander Kros, Wim Jiskoot

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要旨

In this study poly(γ-benzyl-L-glutamate)-K (PBLG50-K) polymersomes are tested as an immune adjuvant for an antigen, influenza hemagglutinin (HA). The polymersomes were prepared according to a solvent removal method and loaded with HA antigensvia adsorption. The immunogenicity of the resulting hybrid assemblies was tested in vivo, resulting in an improvement of the immune response for the influenza antigen co-administered with the polymersomes.

掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Polymersomes enhance the immunogenicity of influenza subunit vaccine

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