Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles

文献情報

出版日 2009-08-11

DOI 10.1039/B911353C

インパクトファクター 6.222

著者

Vincent J. Venditto, Kimberly Allred, Clinton D. Allred, Eric E. Simanek

原文を見る

要旨

The camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

掲載誌

Chemical Communications

CiteScore: 8.6

自己引用率: 4.7%

年間論文数: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles

文献情報

おすすめジャーナル

関連文献

Asymmetric epoxidation of 2-arylidene-1,3-diketones: facile access to synthetically useful epoxides

An efficient entry to 1,2-benzisoxazoles via1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

Linear and nonlinear photophysics and bioimaging of an integrin-targeting water-soluble fluorenylprobe

Abiesatrines A–J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr

Two-dimensional self-organization of rectangular OPE amphiphiles into microcrystalline lamellae

Photosensitized cleavage of plasmidic DNA by norharmane, a naturally occurring β-carboline

Understanding the mechanism of stereoselective synthesis of cyclopentenes viaN-heterocyclic carbene catalyzed reactions of enals with enones

Long wavelength red fluorescent dyes from 3,5-diiodo-BODIPYs

Theoretical investigations on the formation of nitrobenzanthrone-DNA Adducts

Highly selective fluorescent probe for Au3+ based on cyclization of propargylamide

こちらもおすすめ

環戊烷-1,3-二甲酸甲酯はどのように合成されますか？

4-メトキシ-1,2,3-スチアゼ-3,5-ジオンとは何ですか？

プロスタグランジンA2について「に適用される法規ガイドラインは何ですか？'

4-アミノ-1-ナフタレン sulfonic 酸についての物理化学的性質は何ですか？

N-GlcNAc-生物素を取り扱う際の実験室安全事項は何ですか？

3-アミノメチルフローラノピペリジン-1-カルボニル酸テルブチルエステルとは何ですか？

6-溴-1-甲基-1H-ベンゾ[d][1,2,3]三氮唑はどのように合成されますか？

4-硫代尿苷はどのように合成されますか？

ブレインナトリユリックペプチド32ラットとは何ですか？

1-(3-氮杂啶)-4-羟基哌啶双盐酸盐の物理化学的性質は何ですか？

掲載誌

Chemical Communications

おすすめ化合物

5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine hydrochloride (1:1)

5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde

Cytochalasin E

4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl acetate

Ethyl (2-methyl-1H-indol-3-yl)acetate

おすすめサプライヤー