Ca2+ enhanced catalytic NADH oxidation: a coupled 31P-NMR and electrochemistry study

文献情報

出版日 2003-04-17

DOI 10.1039/B212605B

インパクトファクター 3.676

著者

Nicolas Mano, Alexander Kuhn, Stéphane Menu, Erick J. Dufourc

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要旨

The Ca2+-promoted 500% increase in activity of nitrofluorenone modified electrodes towards NADH oxidation is studied by 31P-NMR. The interaction of Ca2+ with NADH on the one hand and with the redox mediator on the other hand, results in a conformational change of the coenzyme. This event occurs concomitantly with the observed current increase. A three-member complex, in which Ca2+ bridges a NADH phosphate and the carboxyl group of the mediator is proposed as the molecular key for the potentiation of the electrocatalytic current.

掲載誌

Physical Chemistry Chemical Physics

CiteScore: 5.5

自己引用率: 10.3%

年間論文数: 3036

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