Stabilization of planar lipid membranes: A stratified layer approach
文献情報
Wolfgang Meier, Alexandra Graff, Anke Diederich, Mathias Winterhalter
Here we briefly summarize our recent efforts in stabilization of giant planar lipid membranes and provide the first promising results achieved with a new technique. A water-soluble polymer can be coupled to lipid membranes either electrostatically or ia a hydrophobic linker. Such coated membranes are significantly destabilized and the rupture process is slowed down. In contrast, partitioning of hydrophobic styrene monomer into the lipid membrane and its polymerization lead to an increase in stability. A short electric field pulse under controlled conditions was applied to quantify the stability. Voltages above 1.2 V are required to induce an electrical discharge. Within less than 100 μs these defects reseal. However, after resealing, the stability of this particular lipid membrane corresponds to that of a lipid membrane without a 2-D polymer network. We suggest the use of this technique to stabilize self-assembled lipid membrane structures.
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Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.










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