化合物よくある質問
MK-0812（ Succinate）はどのように合成されますか？
回答
![Succinic acid - 1,5-anhydro-2,3-dideoxy-3-{[(1S,3R)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]amino}-4-O-methyl-D-erythro-pentitol (1:1)](https://static.chemtradehub.com/structs/851/851916-42-2-72d5.webp "Succinic acid - 1,5-anhydro-2,3-dideoxy-3-{[(1S,3R)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]amino}-4-O-methyl-D-erythro-pentitol (1:1)")
MK-0812（ Succinate）は、（1S,3R）-3-イソプロピル-3-{[3- trifluoromethyl-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl} cyclopentyl} amino}-4-O-メチル-D-エリスロ-ペンチトール（1:1）と succinic acid を使用して合成できます。これは複雑な合成反応であり、触媒の選択と反応条件の最適化が必要です。
について
CAS番号
851916-42-2
英語名前
Succinic acid - 1,5-anhydro-2,3-dideoxy-3-{[(1S,3R)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]amino}-4-O-methyl-D-erythro-pentitol (1:1)
分子式
C28H40F3N3O7
分子量
587.63 g/mol
SMILES
OC(=O)CCC(=O)O.CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2c(C1)cc(cn2)C(F)(F)F
InChIKey
WPPJJJUIDYHHSM-PXUYIWLPSA-N
最後の更新: 2026-03-04 16:30
![Succinic acid - 1,5-anhydro-2,3-dideoxy-3-{[(1S,3R)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]amino}-4-O-methyl-D-erythro-pentitol (1:1) — MedChemExpress LLC](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp){kind=logo}
![Succinic acid - 1,5-anhydro-2,3-dideoxy-3-{[(1S,3R)-3-isopropyl-3-{[3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl]carbonyl}cyclopentyl]amino}-4-O-methyl-D-erythro-pentitol (1:1) — ShangHaiChuangSai Technology Co Ltd](https://static.chemtradehub.com/suppliers/67cecce82b2de6e8e95a5e02/67cecce82b2de6e8e95a5e02-logo.webp){kind=logo}