化合物よくある質問
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OHはどのように合成されますか？
回答
![(23S,50S)-50-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,2-dimethyl-23-{[(2-methyl-2-propanyl)oxy]carbonyl}-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
(non-preferred name)](https://static.chemtradehub.com/structs/166/1662688-20-1-2160.webp "(23S,50S)-50-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,2-dimethyl-23-{[(2-methyl-2-propanyl)oxy]carbonyl}-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
(non-preferred name)")
Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OHは、Fmoc保護基を有するL-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]が原料とし、purGエンジンered L-氨基酸アミド合成反応を経て合成されます。一般的には、触媒と選択性の高い反応条件が必要で、収率は約80～90%です。CAS番号は1662688-20-1です。
について
CAS番号
1662688-20-1
英語名前
(23S,50S)-50-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,2-dimethyl-23-{[(2-methyl-2-propanyl)oxy]carbonyl}-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
(non-preferred name)
分子式
C64H101N5O16
分子量
1196.53 g/mol
SMILES
CC(C)(C)OC(=O)[C@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(O)=O)NC(=O)CCCCCCCCCCCCCCCCC(=O)OC(C)(C)C
InChIKey
COTQASXXEXJBOM-PJYGOTMFSA-N
最後の更新: 2025-11-07 19:01
![(23S,50S)-50-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,2-dimethyl-23-{[(2-methyl-2-propanyl)oxy]carbonyl}-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
(non-preferred name) — 张家界恒康生物药业有限公司](https://static.chemtradehub.com/suppliers/67cdfb6057537e5c8069b0a1/67cdfb6057537e5c8069b0a1-logo.webp){kind=logo}
![(23S,50S)-50-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2,2-dimethyl-23-{[(2-methyl-2-propanyl)oxy]carbonyl}-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
(non-preferred name) — 北京中硕医药科技開発有限公司](https://static.chemtradehub.com/suppliers/67cdf59457537e5c8069b02c/67cdf59457537e5c8069b02c-logo.webp){kind=logo}