化合物よくある質問
N-乙酰基-5`-O-[双(4-甲氧基苯基)苯基甲基]-2`-脱氧-2`-氟胞苷はどのように合成されますか？
回答
![N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine](https://static.chemtradehub.com/structs/159/159414-98-9-6e0d.webp "N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine")
N-乙酰基-5`-O-[双(4-甲氧基苯基)苯基甲基]-2`-脱氧-2`-氟胞苷は、5'-O-[双(4-甲氧基苯基)苯基甲基]-2`-脱氧-2`-氟胞苷にN-乙酰化反応を行なうことで得られます。この反応は通常、酸性条件で触媒を使用して行われ、選択性は高いですが、収率は約80%です。
について
CAS番号
159414-98-9
英語名前
N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorocytidine
分子式
C32H32FN3O7
分子量
589.62 g/mol
SMILES
CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)F
InChIKey
JIFNUYITABZZQS-PYYPWFDZSA-N
最後の更新: 2025-10-22 19:24
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