化合物よくある質問
盐酸纳美芬是如何合成的？
回答
![(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride](https://static.chemtradehub.com/structs/588/58895-64-0-6c55.webp "(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride")
盐酸纳美芬通常通过合成苯并呋喃并异喹啉骨架，然后引入所需的官能团来制备。具体的合成方法包括使用环合反应、取代反应和还原反应。通常会使用有机溶剂，如二氯甲烷或四氢呋喃，并在适当条件下使用催化剂，如钯或铑。最终产物通过重结晶提纯，收率约为80%。
について
CAS番号
58895-64-0
英語名前
(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride
分子式
C21H26ClNO3
分子量
375.9 g/mol
SMILES
C=C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O.Cl
InChIKey
GYWMRGWFQPSQLK-OPHZJPRHSA-N
最後の更新: 2025-10-22 12:37
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![(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylene-1,2,3,4,5,6,7,7a-octahydro-4aH-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol hydrochloride — 武汉丰泰威远科技有限公司](https://static.chemtradehub.com/suppliers/67cebe962b2de6e8e95a4b59/67cebe962b2de6e8e95a4b59-logo.webp){kind=logo}