化合物よくある質問
托伐普坦はどのように合成されますか？
回答
![N-{4-[(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide](https://static.chemtradehub.com/structs/150/150683-30-0-d18c.webp "N-{4-[(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide")
托伐普坦通常通过多步有机合成方法制备，包括酰化反应、环合反应、以及还原反应等。合成路线中使用了如三氟乙酸酐、N-甲基吗啉等试剂作为酰化剂和溶剂，总收率约为50%左右。
について
CAS番号
150683-30-0
英語名前
N-{4-[(7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl}-2-methylbenzamide
分子式
C26H25ClN2O3
分子量
448.95 g/mol
SMILES
CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
InChIKey
GYHCTFXIZSNGJT-UHFFFAOYSA-N
最後の更新: 2025-09-09 08:06
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