Catalyst-free assembly of a polyfunctionalized 1,2,4-triazole-fused N-heterocycle, 6-acylated pyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine

文献情報

出版日 2023-11-29

DOI 10.1039/D3OB01747H

インパクトファクター 3.876

著者

Hyunjin Oh, Ikyon Kim

原文を見る

要旨

A catalyst-free synthetic route to a new 1,2,4-triazole-pyrrolo[1,2-a]pyrazine hybrid system, 6-acylpyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine, was realized upon sequential exposure of pyrrole-2-carbonitrile-derived substrates to DMF-DMA and acyl hydrazide through which acylated pyrazine and 1,2,4-triazole rings were consecutively formed with the formation of multiple bonds (one C–C bond and three C–N bonds). This annulative functionalization approach towards N-fused polycycles enabled us to install various substituents at specific positions on the core skeleton.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Catalyst-free assembly of a polyfunctionalized 1,2,4-triazole-fused N-heterocycle, 6-acylated pyrrolo[1,2-a][1,2,4]triazolo[5,1-c]pyrazine

文献情報

おすすめジャーナル

関連文献

Using high-throughput virtual screening to explore the optoelectronic property space of organic dyes; finding diketopyrrolopyrrole dyes for dye-sensitized water splitting and solar cells

Front cover

Rationally constructing nitrogen–fluorine heteroatoms on porous carbon derived from pomegranate fruit peel waste towards an efficient oxygen reduction catalyst for polymer electrolyte membrane fuel cells

Morphologically controlled rapid fabrication of rhodium sulfide (Rh2S3) thin films for superior and robust hydrogen evolution reaction

CoOx electro-catalysts anchored on nitrogen-doped carbon nanotubes for the oxygen evolution reaction

Methane synthesis from CO2 and H2O with electricity using H-permeable membrane electrochemical cells with Ru catalyst and phosphate electrolyte

Phase-controllable polymerized ionic liquids for CO2 fixation into cyclic carbonates

An efficient hybrid supercapacitor based on Zn–Mn–Ni–S@NiSe core–shell architectures

Simulation of bi-layer cathode materials with experimentally validated parameters to improve ion diffusion and discharge capacity

Highly active and stable Ni/perovskite catalysts in steam methane reforming for hydrogen production

こちらもおすすめ

5-苄基四氢吡咯并[3,4-c]吡咯-1,3[2H,3ah]-二酮の主な用途は何ですか？

唾液酸路易ス Aを取り扱う際の実験室安全事項は何ですか？

タルトブチル ((1-(2-クロロアセチル)ピペリジン-4-イルメチル)カーバamatはどの業界で使用されていますか？

3-烯丙基-2-羟基苯甲醛の物理化学的性質は何ですか？

乳清酸 Potassium Orotateとは何ですか？

4-甲基苯磺酸异丙酯はどの業界で使用されていますか？

6-(3- Florobenzen)-N-[1-(2,2,2- Trifluoroethyl)-4-Piperidinyl]-3-Pyridinycarboxamideはどの業界で使用されていますか？

左西孟旦はどのように合成されますか？

3-乙氧基哌啶盐酸盐に適用される法規ガイドラインは何ですか？

Diethyl (hydroxymethyl)phosphonateの主な用途は何ですか？

掲載誌

Organic & Biomolecular Chemistry

おすすめ化合物

2-Methyl-2-propanyl 4-[3-(aminomethyl)phenyl]-1-piperazinecarboxylate

Homovanillic Acid-d3

TPh A

9-Ethyl-3-{(E)-[ethyl(2-methylphenyl)hydrazono]methyl}-9H-carbazole

Dicyclopropylmethanol

おすすめサプライヤー