Selective and controllable amination and defluoroamidation of α-trifluoromethylstyrene

文献情報

出版日 2023-10-21

DOI 10.1039/D3OB01595E

インパクトファクター 3.876

著者

Shuang-Lian He, Yong-Sheng Bao, Juan Hu, Chaolumen Bai, Dan Liu

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要旨

We present a blueprint for the amination and defluoroamidation of α-trifluoromethylstyrene. This practical protocol presents a general method for the diversity-oriented synthesis of vicinal trifluoromethyl amines and gem-difluoro alkenes from α-trifluoromethylstyrene maintaining excellent chemoselectivity. The synthetic strategy features outstanding atom economy and wide functional group tolerance under mild reaction conditions.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Selective and controllable amination and defluoroamidation of α-trifluoromethylstyrene

文献情報

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