Effect of surface acidity and basicity of supported Ni catalysts on the N-alkylation of isopropylamine with isopropanol
文献情報
Shaozhong Li, Qing Guo, Jin Li, Yongke Hu
The N-alkylation of amines with alkylating reagents is widely used in the synthesis of aliphatic amines, which is usually catalyzed by homogeneous catalytic systems. In this work, the heterogeneous catalysts Ni/AlSiO (NAS), Ni/LaAlSiO (NLAS) and Ni/LaO (NL) with different strengths of acidity and basicity were used in the N-alkylation of isopropylamine (IPA) with isopropanol (IPO) to diisopropylamine (DIPA) in a fixed-bed reactor, and the effect of surface acidity and basicity of the supported Ni catalysts on the N-alkylation was studied by microcalorimetric adsorption and in situ Fourier transform infrared spectra. It was found that the surface acidity and basicity of the supported Ni catalysts affected the adsorption and interaction of IPO, IPA and DIPA on the supported Ni catalysts, and IPO and IPA molecules were strongly adsorbed onto the strong acidic surface, which would improve the N-alkylation reaction. In addition, the generation of imine species from the dehydrogenation of IPA greatly decreased the activity of the N-alkylation reaction, and the strong adsorption of dissociated H from the adsorption of IPO, IPA or DIPA on acidic surface inhibited the generation of imine species, which promoted the conversion of IPA. Meanwhile, the strong adsorption of dissociated H on acidic surface also promoted the hydrogenation of diisopropylimine, which increased the selectivity to DIPA.
関連文献
Development of silver film viathermal decomposition of layered silver alkanecarboxylates for surface-enhanced Raman spectroscopy
Seung Joon Lee, Kwan Kim
DOI: 10.1039/B210217J
Production, isolation and structural characterization of [92]fullerene isomers
Denis Arcon, Maurizio Prato, Hisanori Shinohara
DOI: 10.1039/B208820G
Potential-controlled switching of 2-(2′-thienyl)pyridine adsorbed on Au(111)
Emily Chung, Dan Bizzotto, Michael O. Wolf
DOI: 10.1039/B208912B
Electrochemical synthesis of novel polypyrrole microstructures
Liangti Qu, Gaoquan Shi
DOI: 10.1039/B209245J
Novel intermolecular carbon radical addition to a nitrone: asymmetric synthesis of α-amino acids
Masafumi Ueda, Hideto Miyabe, Masako Teramachi, Okiko Miyata, Takeaki Naito
DOI: 10.1039/B211570K
Formation and structural observation of cesium encapsulated single-walled carbon nanotubes
Goo-Hwan Jeong, Rikizo Hatakeyama, Takamichi Hirata, Kazuyuki Tohji, Kenichi Motomiya, Toshie Yaguchi, Yoshiyuki Kawazoe
DOI: 10.1039/B210079G
Novel bis-acac-O,O–Ir(iii) catalyst for anti-Markovnikov, hydroarylation of olefins operates by arene CH activation
Roy A. Periana, Xiang Y. Liu, Gaurav Bhalla
DOI: 10.1039/B208680H
Functionalized heteropolyanions: high-valent metal nitrido fragments incorporated into a Keggin polyoxometalate structure
Haidoo Kwen, Sean Tomlinson, Eric A. Maatta, Céline Dablemont, René Thouvenot, Anna Proust, Pierre Gouzerh
DOI: 10.1039/B209173A
Conformational landscape surfing induced by off–on π–π stacking in a porphyrin–quinone dyad
Kevin M. Smith
DOI: 10.1039/B209238G
Silver nanoparticle growth in 3D-hexagonal mesoporous silica films
Thierry Gacoin, Christian Ricolleau, Jean-Pierre Boilot
DOI: 10.1039/B208357D
こちらもおすすめ
3-イチチルビフェニルはどのように合成されますか?
3-イチチルビフェニルは、ビフェニルとイチプロピオニトリルを回収率約90%で反応させて合成されます。触媒は通常、亜リチウムホウ素を用います。
8-溴-5-三氟甲基喹啉はどのように合成されますか?
8-溴-5-三氟甲基喹啉は、5-トリフルオロメチル-2-メチル-1,3-ベンゼンジオールをブロモエタノールと反応させて生成します。この反応は塩基性条件下で行われ...
ジメチル4-(4,4,5,5-テトラメチル-1,3,2-ドioxaborolan-2-基)-2,6-ピリジンジカルボイル酸フェニルアミニドの代替品はありますか?
ジメチル4-(4,4,5,5-テトラメチル-1,3,2-ドioxaborolan-2-基)-2,6-ピリジンジカルボイル酸フェニルアミニドの代替品としては、4-...
N-(3,5-ヘキサクロロ-4-ピリドインイル)-8-メチオキシ-5-キノリンカーボン酸の市場動向や研究トレンドはどのようなものでしょうか?
N-(3,5-ヘキサクロロ-4-ピリドインイル)-8-メチオキシ-5-キノリンカーボン酸の市場動向は、主に産業用途での需要により影響を受けます。研究トレンドとし...
イソステアロイルグリセリルは安全ですか?
イソステアロイルグリセリルは一般的に安全性が高いとされていますが、過度な使用や個人差により皮�owsん炎などの反応が起こる可能性があります。使用前に医師に相談す...
1-(二苯甲基)-3,3-二氟-氮杂环丁烷の市場動向や研究トレンドはどうですか?
1-(二苯甲基)-3,3-二氟-氮杂环丁烷の市場動向は、医薬品や合成化学の研究分野で注目を集めています。新興研究は、該当化合物の合成改良と生体内での作用メカニズ...
3-チオフェンスチオールの物理化学的性質は何ですか?
3-チオフェンスチオールのCAS番号は7774-73-4です。結晶性の白色粉末で、分子量は122.17です。この化合物は水に微溶解し、エタノールやジクロロメタン...
2-Methyl-2-propanyl (2S)-2-(aminomethyl)-1-piperidinecarboxylateは安全ですか?
2-Methyl-2-propanyl (2S)-2-(aminomethyl)-1-piperidinecarboxylateは一定の安全性基準を満たしていま...
CAS番号1316822-90-8の化合物は安全ですか?
CAS番号1316822-90-8の化合物は安全性に関しては評価が不足していますが、一般的には生物学的に活性な物質であり、取り扱いには適切な安全防護措置が必要で...
Tert-butyl 2-(2-羟基乙基)哌嗪-1-羧酸はどのように保存すればよいですか?
Tert-butyl 2-(2-羟基乙基)哌嗪-1-羧酸は、冷暗所で保存し、直射日光から遠ざけてください。容器は密閉し、高湿度や高温を避けて保管してください。
掲載誌
Reaction Chemistry & Engineering

Reaction Chemistry & Engineering is an interdisciplinary journal reporting cutting-edge research focused on enhancing the understanding and efficiency of reactions. Reaction engineering leverages the interface where fundamental molecular chemistry meets chemical engineering and technology. Challenges in chemistry can be overcome by the application of new technologies, while engineers may find improved solutions for process development from the latest developments in reaction chemistry. Reaction Chemistry & Engineering is a unique forum for researchers whose interests span the broad areas of chemical engineering and chemical sciences to come together in solving problems of importance to wider society. All papers should be written to be approachable by readers across the engineering and chemical sciences. Papers that consider multiple scales, from the laboratory up to and including plant scale, are particularly encouraged.












![1-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one structure 1-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one structure](https://static.chemtradehub.com/structs/603/60373-71-9-7dfb.webp)
![N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-2-(2-propyn-1-yloxy)acetamide structure N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-2-(2-propyn-1-yloxy)acetamide structure](https://static.chemtradehub.com/structs/210/2101206-92-0-2eb5.webp)
