Characterization of the promiscuous N-acyl CoA transferase, LgoC, in legonoxamine biosynthesis

文献情報

出版日 2020-03-04

DOI 10.1039/D0OB00320D

インパクトファクター 3.876

著者

Justine Renault, Laurent Trembleau, Catherine Victoria, Ming Him Tong, Shan Wang, Kwaku Kyeremeh, Hai Deng

原文を見る

要旨

More than 500 siderophores are known to date, but only three were identified to be aryl-containing hydroxamate siderophores, legonoxamines A and B from Streptomyces sp. MA37, and aryl ferrioxamine 2 from Micrococcus luteus KLE1011. Siderophores are produced by microorganisms to scavenge iron from the environment, thereby making this essential metal nutrient available to the microbe. We demonstrate here that LgoC from MA37 is responsible for the key aryl-hydroxamate forming step in legonoxamine biosynthesis. Biochemical characterization established that LgoC displays considerable promiscuity for the acylation between N-hydroxy-cadaverine and SNAC (N-acetylcysteamines) thioester derivatives.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Characterization of the promiscuous N-acyl CoA transferase, LgoC, in legonoxamine biosynthesis

文献情報

おすすめジャーナル

関連文献

A functional electrolyte containing propyl 4-methylbenzene sulfonate (PMBS) additive to improve the cycling performance of the LiNi0.8Co0.1Mn0.1O2/graphite full cell under the low temperature of −10 °C

Front cover

Building fast and selective Zn ion channels for highly stable quasi-solid-state Zn-ion batteries

Correction: Hydrothermal synthesis of α-MnO2 and β-MnO2 nanorods as high capacity cathode materials for sodium ion batteries

Rapidly tuning the electrocatalytic activity of perovskite oxides by plasma treatment

Enhancing SERS activity with a pyroelectric-induced charge-transfer effect

Mechanical disassembly of human picobirnavirus like particles indicates that cargo retention is tuned by the RNA–coat protein interaction

Simple phenylpropanoids: recent advances in biological activities, biosynthetic pathways, and microbial production

Coke relocation and Mo immobilization in donut-shaped Mo/HZSM-5 catalysts for methane dehydroaromatization

Sublimation-based wafer-scale monolayer WS2 formation via self-limited thinning of few-layer WS2

こちらもおすすめ

アエポキシアビレーターONE酢酸エステルを含む廃棄物はどのように処理すべきですか？

4-ヒドロキシ但線を取り扱う際の実験室安全事項は何ですか？

4-(3-環戊基尿素)フェノールボロネートはどの業界で使用されていますか？

N~1~-[3-氯-5-(三氟甲基)-2-吡啶]-1,2-乙二胺の市場動向や研究トレンドはどうですか？

6-硝基苯并二氢吡喃-4-酮についての法規ガイドラインは何ですか？

5-(肼甲基)-2-甲基吡啶の主な用途は何ですか？

6-乙酰基-2(3H)-苯并噻唑酮は安全ですか？

3-メチル-6-(1-メチルヒドラジニル)ピリジジンはどの業界で使用されていますか？

tert-butyl 5-oxo-2,6-diazaspiro[3.4]octane-2-carboxylateの物理化学的性質は何ですか？

3-塩素メチルフェニル-4,4,5,5-テトラメチル-1,3,2-ジオキソボロラノールは安全ですか？

掲載誌

Organic & Biomolecular Chemistry

おすすめ化合物

4,5,6,7-Tetrahydro-2H-indazole

(3R)-4-(4-Chlorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butanoic acid

4-(Dicyclohexylphosphino)-N,N-dimethylaniline

2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline

Benzophenonetetracarboxylic acid

おすすめサプライヤー