Oxidant-controlled divergent transformations of 3-aminoindazoles for the synthesis of pyrimido[1,2-b]-indazoles and aromatic nitrile-derived dithioacetals

文献情報

出版日 2019-08-09

DOI 10.1039/C9QO00847K

インパクトファクター 5.281

著者

Yao Zhou, Yixian Lou, Ya Wang

原文を見る

要旨

The oxidant-controlled divergent reactivity of 3-aminoindazoles is presented herein. Diverse functionalized pyrimido[1,2-b]-indazole derivatives were obtained with good yields via a Lewis-acid promoted [3 + 3] annulation reaction between ketene dithioacetals and 3-aminoindazoles. When the reaction was performed using the Cu/[O] catalytic system, new reactivity for the ring-opening of 3-aminoindazoles via C–N bond activation was achieved, which enables the olefinic C–H arylation of ketene dithioacetals under mild conditions.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Oxidant-controlled divergent transformations of 3-aminoindazoles for the synthesis of pyrimido[1,2-b]-indazoles and aromatic nitrile-derived dithioacetals

文献情報

おすすめジャーナル

関連文献

Fabrication of superhydrophilic–underwater superoleophobic inorganic anti-corrosive membranes for high-efficiency oil/water separation

Why solid oxide cells can be reversibly operated in solid oxide electrolysis cell and fuel cell modes?

Interactions of hydrogen with the iron and iron carbide interfaces: a ReaxFF molecular dynamics study

Spatial frequency heterodyne imaging of aqueous phase transitions inside multi-walled carbon nanotubes

Probing electrode/electrolyte interfaces in situ by X-ray spectroscopies: old methods, new tricks

Inside front cover

Physicochemical perspectives (aggregation, structure and dynamics) of interaction between pluronic (L31) and surfactant (SDS)

Tetraalkylammonium interactions with dodecyl sulfate micelles: a molecular dynamics study

S-doped mesoporous nanocomposite of HTiNbO5 nanosheets and TiO2 nanoparticles with enhanced visible light photocatalytic activity

Theoretical modeling of the L2,3-edge X-ray absorption spectra of Mn(acac)2 and Co(acac)2 complexes‡

こちらもおすすめ

3-(2-オキサプロピル)ベンzoic酸はどのように合成されますか？

BOC-L-3-氟苯丙氨酸の主な用途は何ですか？

4-メチル-4-ピペリジニル-1-ピロリドイン甲酸の主な用途は何ですか？

Biotin-PEG3-oxyamine HCl塩について、適切な化合物名称に適用される法規ガイドラインは何ですか？

N-(4-イソチオシアネートフェニル)-2-メトキシアリニンはどのように合成されますか？

金粉蕨亭2'-O-葡萄糖甙の主な用途は何ですか？

2-(2-ニトロフェニル)酢酸ヒドライドの物理化学的性質は何ですか？

5-(ヒドロキシメチル)-2-チオキソ-2,3-ジヒドロピリミジン-4(1H)-オンを取り扱う際の実験室安全事項は何ですか？

11-脱氢血栓烷 b2の市場動向や研究トレンドはどうですか？

3,3-二甲基哌啶-4-酮はどのように保存すればよいですか？

掲載誌

Organic Chemistry Frontiers

おすすめ化合物

2-Methyl-2-propanyl (2R)-2-formyl-1-piperidinecarboxylate

Chloro(methyldiphenylphosphine)gold(I)

Ethyl 6-(trifluoromethyl)pyridazine-3-carboxylate

4-Iodopentylbenzene

4-Butylpiperidine hydrochloride (1:1)

おすすめサプライヤー