Thiol substrate-promoted dehydrogenative cyclization of arylmethyl thiols with ortho-substituted amines: a universal approach to heteroaromatic compounds

文献情報

出版日 2019-06-15

DOI 10.1039/C9QO00554D

インパクトファクター 5.281

著者

Mengjun Qiao, Ling Chen, Yibo Dong, Chengkang Jiao, Shengqi Liao

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要旨

A thiol substrate-promoted one-pot synthesis of a library of heteroaromatic compounds was developed. Benzo[d]oxazole, benzo[d]thiazole, benzo[d]imidazole, oxazolo[4,5-b]pyridine and naphtho[2,3-d]oxazole derivatives were obtained under metal-free and external oxidant-free conditions in moderate to excellent yields. Commercially available substrates and the absence of supplemental catalysts, oxidants or additives make this method both practical and efficient.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

Thiol substrate-promoted dehydrogenative cyclization of arylmethyl thiols with ortho-substituted amines: a universal approach to heteroaromatic compounds

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