Mitsunobu-initiated cascade cyclization of p-quinamines and 2-furanylmethanols: highly regio- and diastereoselective synthesis of functionalized hydrobenzo[c,d]indoles

文献情報

出版日 2019-03-20

DOI 10.1039/C9OB00585D

インパクトファクター 3.876

著者

Bo Cao, Yin Wei

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要旨

A cascade cyclization of para-quinamines and 2-furanylmethanol has been achieved, affording a series of functionalized hydrobenzo[c,d]indoles in moderate to good yields and excellent diastereoselectivities under mild conditions. This reaction was first initiated by the Mitsunobu reaction and then followed by the [4 + 2] Diels–Alder reaction to furnish the important indole-fused heterocyclic derivatives.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Mitsunobu-initiated cascade cyclization of p-quinamines and 2-furanylmethanols: highly regio- and diastereoselective synthesis of functionalized hydrobenzo[c,d]indoles

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Organic & Biomolecular Chemistry

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