Dinuclear zinc synergistic catalytic asymmetric phospha-Michael/Michael cascade reaction: synthesis of 1,2,3-trisubstituted indanes bearing phosphoryl groups
文献情報
Bing-Kai Tao, Hua Yang, Yuan-Zhao Hua, Min-Can Wang
A new dinuclear zinc synergistic catalytic asymmetric phospha-Michael/Michael cascade reaction of o-dienones and dialkyl phosphates is reported. This method has been proven to be general and efficient for the formation of a range of chiral 1,2,3-trisubstituted indane compounds containing phosphorus groups in good yields (up to 92%) with excellent stereoselectivities (up to >99% ee and up to >99 : 1 dr). The relative configuration of the product was identified as having a trans,trans substitution pattern via two-dimensional (2D) nuclear Overhauser effect spectroscopy 1H–1H NMR experiments. A possible mechanism was proposed.
関連文献
Solid-state NMR as a probe of anion binding: molecular dynamics and associations in a [5]polynorbornane bisurea host complexed with terephthalate
Aditya Rawal, James M. Hook, Ryan N. Robson, Daniel Gunzelmann, Frederick M. Pfeffer, Luke A. O'Dell
DOI: 10.1039/C5CP03628C
Magneto-thermally activated spin-state transition in La0.95Ca0.05CoO3: magnetically-tunable dipolar glass and giant magneto-electricity
Suchita Pandey, Jitender Kumar, A. M. Awasthi
DOI: 10.1039/C5CP06932G
Temperature-dependent nanomorphology–performance relations in binary iridium complex blend films for organic light emitting diodes
Young-Tae Kim, Young-Hoon Kim, Tae-Woo Lee
DOI: 10.1039/C5CP03436A
Quantum dynamical investigation of the isotope effect in H2 formation on graphite at cold collision energies
Marta Pasquini, Matteo Bonfanti
DOI: 10.1039/C5CP07272G
Electrochemical ‘bubble swarm’ enhancement of ultrasonic surface cleaning
P. R. Birkin, D. G. Offin, C. J. B. Vian, T. G. Leighton
DOI: 10.1039/C5CP02933C
Molecular dynamics simulations of the atom packing characteristics of three deformed silver nanoparticles at room temperature
DOI: 10.1039/C6CP00188B
The effect of water on the binding of glycosaminoglycan saccharides to hydroxyapatite surfaces: a molecular dynamics study
Ian Streeter
DOI: 10.1039/C5CP02630J
Phosphorylation promotes Al(iii) binding to proteins: GEGEGSGG as a case study
Rafael Grande-Aztatzi, Elena Formoso, Jon I. Mujika, Jesus M. Ugalde, Xabier Lopez
DOI: 10.1039/C5CP06379E
Magnetic susceptibility of actinide(iii) cations: an experimental and theoretical study
Matthieu Autillo, Laetitia Guerin, Hélène Bolvin, Philippe Moisy, Claude Berthon
DOI: 10.1039/C5CP07456H
Tuning the charge state of Ag and Au atoms and clusters deposited on oxide surfaces by doping: a DFT study of the adsorption properties of nitrogen- and niobium-doped TiO2 and ZrO2
Philomena Schlexer, Antonio Ruiz Puigdollers, Gianfranco Pacchioni
DOI: 10.1039/C5CP03834K
こちらもおすすめ
2,5-二羧基氟苯の市場動向や研究トレンドはどうですか?
2,5-二羧基氟苯の市場は、主に医薬品および農薬の研究開発において伸長しています。一方、環境への影響や安全性の懸念から、その使用は一定の制限が置かれています。今...
8-甲基-2-噻吩-2-基-喹啉-4-羧酸を含む廃棄物はどのように処理すべきですか?
8-甲基-2-噻吩-2-基-喹啉-4-羧酸を含む廃棄物は専門的な廃棄処理が必要です。具体的には、廃棄物は密閉の容器に収集し、適切な危険物対策を講じて専門業者に引...
2-(1,3-二氧杂烷-2-基)噻唑の物理化学的性質は何ですか?
CAS番号24295-04-3の2-(1,3-二氧杂烷-2-基)噻唑は、結晶形態により白色粉末を呈します。分子量は208.23 g/molであり、水に溶けにくい...
L-beta-高酪氨酸塩酸塩は安全ですか?
L-beta-高酪氨酸塩酸塩自体は毒性は低く、しかし使用する際は適切な個人保護具を使用し、誤飲や皮膚への接触を避けることが推奨されます。
睡茄灯笼草素Cはどのように合成されますか?
睡茄灯笼草素Cは、シクラメンケチャナfromaceaeから抽出する方法や、化学合成法で合成することができます。典型的な化学合成法では、3β,22-二オキシエクス...
4-(嘧啶-2-基)哌嗪-1-羧酸叔丁酯はどのように保存すればよいですか?
4-(嘧啶-2-基)哌嗪-1-羧酸叔丁酯は直射日光を避けて、室温で保存するのが良いです。湿度を避けて密閉容器に入れて保管し、未使用の状態で長期保存することができ...
NBI-74330の主な用途は何ですか?
NBI-74330は主に薬理学研究および医療用途に使用されています。その主な用途は抗がん作用を有するため、がん治療の研究に使用されています。
6-トリフルオロメチル-2-クロロピリジン-4-ボリリック酸はどのように合成されますか?
6-トリフルオロメチル-2-クロロピリジン-4-ボリリック酸は、6-トリフルオロメチル-2-クロロピリジンとボリルリチウムを触媒なしで反応させることで合成するこ...
掲載誌
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.










![4-{1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropyl}morpholine structure 4-{1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropyl}morpholine structure](https://static.chemtradehub.com/structs/120/1206594-08-2-7afb.webp)


![9,9'-Spirobi[fluoren]-2-amine structure 9,9'-Spirobi[fluoren]-2-amine structure](https://static.chemtradehub.com/structs/118/118951-68-1-0d14.webp)
