Selective nickel-catalyzed dehydrogenative–decarboxylative formylation of indoles with glyoxylic acid

文献情報

出版日 2018-04-30

DOI 10.1039/C8OB00810H

インパクトファクター 3.876

著者

Zhiping Yin, Zechao Wang, Xiao-Feng Wu

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要旨

Herein we present a new strategy for the dehydrogenative–decarboxylative coupling of indoles with glyoxylic acid. A broad range of indoles were transformed into the corresponding 3-formylindoles in moderate to good yields and excellent functional group tolerance. Notably, no N-formylation product was detected under our conditions.

掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

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