Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters via C–N bond activation

文献情報

出版日 2018-04-04

DOI 10.1039/C8OB00488A

インパクトファクター 3.876

著者

Weijie Yu, Shuwu Yang, Fei Xiong, Tianxiang Fan, Yan Feng, Yuanyuan Huang, Junkai Fu, Tao Wang

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要旨

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C–N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.

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掲載誌

Organic & Biomolecular Chemistry

CiteScore: 3.4

自己引用率: 10.3%

年間論文数: 1041

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters via C–N bond activation

文献情報

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