Exploiting the conformational-selection mechanism to control the response kinetics of a “smart” DNA hydrogel

文献情報

出版日 2018-04-24

DOI 10.1039/C8AN00337H

インパクトファクター 4.616

著者

Anna J. Simon, Luke T. Walls-Smith

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要旨

The sequence-specific hybridization and molecular recognition properties of DNA support the construction of stimulus-responsive hydrogels with precisely controlled crosslink geometry. Here we show that, as predicted by the conformational selection mechanism, the response kinetics of such a hydrogel can be tuned over orders of magnitude by modulating the thermodynamic stability of its crosslinks.

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CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

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Exploiting the conformational-selection mechanism to control the response kinetics of a “smart” DNA hydrogel

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