Ratiometric fluorescence monitoring of cerebral Cu2+ based on coumarin-labeled DNA coupled with the Cu2+-induced oxidation of o-phenylenediamine

文献情報

出版日 2017-08-04

DOI 10.1039/C7AN01099K

インパクトファクター 4.616

著者

Shishi Ma, Qiao-Yu Zhou, Fang-Ya Mu, Zi-Han Chen, Xu-Yin Ding, Min Zhang, Guoyue Shi

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要旨

A novel and facile ratiometric fluorescence method for evaluating Cu2+ has been developed based on coumarin-labeled single-stranded DNA (C-ssDNA) coupled with the Cu2+-induced oxidation of o-phenylenediamine (OPD). By combining the microdialysis technique, the ratiometric fluorescence method has also been successfully exploited to monitor the cerebral Cu2+ in the rat brain, promising new opportunities for studying the cerebral Cu2+-associated physiological and pathological events.

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CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

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Ratiometric fluorescence monitoring of cerebral Cu2+ based on coumarin-labeled DNA coupled with the Cu2+-induced oxidation of o-phenylenediamine

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