An array of individually addressable micro-needles for mapping pH distributions

文献情報

出版日 2016-05-11

DOI 10.1039/C6AN00639F

インパクトファクター 4.616

著者

Claudio Zuliani, Fu Siong Ng, Andrea Alenda, Amir Eftekhar, Nicholas S. Peters, Christofer Toumazou

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要旨

This work describes the preparation of an array of individually addressable pH sensitive microneedles which are sensitized by electrodepositing iridium oxide. The impact of the deposition potential, storage conditions and interferents on the sensor characteristics such as slope, offset, intra- and inter-batch reproducibility is investigated. The device may be a useful tool for carrying out direct pH measurements of soft and heterogeneous samples such as tissues and organs. For example, we demonstrated that the microneedle array can be employed for real-time mapping of the cardiac pH distribution during cycles of global ischemia and reperfusion.

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CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

An array of individually addressable micro-needles for mapping pH distributions

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