Orderly nucleic acid aggregates by electrostatic self-assembly in single cells for miRNA detection and visualizing

文献情報

出版日 2016-03-29

DOI 10.1039/C6AN00160B

インパクトファクター 4.616

著者

Yuanyuan Wang, Zhaopeng Yu, Zhen Zhang, Shusheng Zhang

原文を見る

要旨

Orderly nucleic acid aggregates (ONAAs) self-assembled on mesoporous silica nanoparticles (MSNs) with positively charged aminopropyl groups (PC) were firstly developed. Interestingly, a novel electrostatic DNA self-assembly could realize hybridization chain reaction (HCR) on the surface of PCMSNs in single cells. Significantly, a non-destructive amplification strategy based on ONAAs-PCMSNs was successfully developed for miRNA detection and in situ imaging by the prominent and agminated fluorescence-bright spots in living cells.

掲載誌

Analyst

CiteScore: 7.8

自己引用率: 5.6%

年間論文数: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

Orderly nucleic acid aggregates by electrostatic self-assembly in single cells for miRNA detection and visualizing

文献情報

おすすめジャーナル

関連文献

Back cover

Lithium sulfur and lithium oxygen batteries: new frontiers of sustainable energy storage

Colloidal synthesis of iridium-iron nanoparticles for electrocatalytic oxygen evolution

Back cover

A synergistic use of microalgae and macroalgae for heavy metal bioremediation and bioenergy production through hydrothermal liquefaction

Efficient conversion of glucose into 5-hydroxymethylfurfural using a bifunctional Fe3+ modified Amberlyst-15 catalyst

High open circuit voltages in pin-type perovskite solar cells through strontium addition

A surfactant-assisted strategy to tailor Li-ion charge transfer interfacial resistance for scalable all-solid-state Li batteries

Contents list

Correction: Mesoporous thin film WO3 photoanode for photoelectrochemical water splitting: a sol–gel dip coating approach

こちらもおすすめ

カルボニル基が付いた5-氰基-1-{[(2-メチル-2-プロpanyl)オキシ]カーボンイル}1H-吲哚-2-イリド-2-ボリン酸はどのように保存すればよいですか？

tert-ブチル2-クロロメチルピリジン-3-基炭酸エステルの市場動向や研究トレンドはどうですか？

聚二季戊四醇六丙烯酸酯はどの業界で使用されていますか？

1-氯-5-硝基异喹啉の市場動向や研究トレンドはどうですか？

2-チロール-5-メチルスルフェニル-3-trifルオルメチルベンゼンはどのように合成されますか？

p-トールイルマグネシウムブロミドの物理化学的性質は何ですか？

1-(5-甲基-2-硫化素基)プロパン-1-酮の市場動向や研究トレンドはどうですか？

十一碳烯酰甘氨酸を取り扱う際の実験室安全事項は何ですか？

1H,1H-全氟-3,6-二氧杂葵-1-醇を取り扱う際の実験室安全事項は何ですか？

3-(4-(フルオロメチルオキシ)フェニル)-1,2,4-オキサジアゾール-5-カルボハイドライドは安全ですか？

掲載誌

Analyst

おすすめ化合物

(3-{[4-(Aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy}phenyl)[(3R,4R)-3-fluoro-4-hydroxy-1-pyrrolidinyl]methanone

2-Methyl-2-propanyl [2-(2-oxa-6-azaspiro[3.3]hept-6-yl)ethyl]carbamate

4-Bromo-5,7-difluoro-1H-indole

N,N'-Bis[3-(2-methoxyphenyl)-2-hydroxybenzyl](1R,2R)-1,2-cyclohexanediamine

2-Methylbenzene-1,3,5-triamine trihydrochloride

おすすめサプライヤー