N-Heterocyclic carbene catalyzed dehydrogenative coupling of enals: synthesis of monobactams

文献情報

出版日 2016-01-07

DOI 10.1039/C5QO00372E

インパクトファクター 5.281

著者

Fangyi Li, Changgui Zhao, Jian Wang

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要旨

The first NHC-catalyzed dehydrogenative coupling of enals is described. With a suitable combination of NHC precatalyst, base, and solvent, the reaction proceeded smoothly to yield a wide range of monobactams. These substituted monobactams have been synthesized for the first time, and they are versatile synthetic intermediates toward other useful complex molecules.

掲載誌

Organic Chemistry Frontiers

CiteScore: 7.8

自己引用率: 8.7%

年間論文数: 724

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

N-Heterocyclic carbene catalyzed dehydrogenative coupling of enals: synthesis of monobactams

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