An injectable drug-loaded hydrogel using a “clickable” amphiphilic triblock copolymer as a precursor

文献情報

出版日 2015-09-24

DOI 10.1039/C5PY01383F

インパクトファクター 5.582

著者

Lilong Gao, Guangyu Zha, Qiaojie Luo, Weipu Zhu, Zhiquan Shen, Xiaodong Li

原文を見る

要旨

We developed a facile strategy to prepare an injectable drug-loaded hydrogel with chemical crosslinkages. A PCL-POEGM-PCL amphiphilic triblock copolymer was synthesized in “one pot” by a combination of polycondensation and ring-opening polymerization, which can disperse hydrophobic drugs in aqueous solution and be crosslinked by POEGMS under physiological conditions.

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掲載誌

Polymer Chemistry

CiteScore: 8.6

自己引用率: 7.3%

年間論文数: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

An injectable drug-loaded hydrogel using a “clickable” amphiphilic triblock copolymer as a precursor

文献情報

おすすめジャーナル

関連文献

Design and examination of an antioxidant-containing polyphosphazene scaffold for tissue engineering

Bulk ring-opening polymerization (ROP) of L-lactide catalyzed by Ni(ii) and Ni(ii)-Sm(iii) complexes based on a salen-type schiff-base ligand

Dixanthate-terminated poly(butylene terephthalate). A novel RAFT/MADIX agent for the synthesis of well-defined triblock copolymers resulting from consecutive step- and chain-growthpolymerization processes

Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

Design and synthesis of new anionic “polymeric ionic liquids” with high charge delocalization

Synthesis of glycopolypeptides by the ring opening polymerization of O-glycosylated-α-amino acid N-carboxyanhydride (NCA)

Investigation of spontaneous emulsification and its relevance in biodiesel synthesis

Electrodeposition and properties of TEMPO functionalized polythiophene thin films

N-Heterocyclic carbene-borane radicals as efficient initiating species of photopolymerization reactions under air

Synthesis of highly porous borazine-linked polymers and their application to H2, CO2, and CH4 storage

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Polymer Chemistry

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